Scientist, Pharmacology Resume Samples

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A Spencer

Alysson

Spencer

28883 Dora Hill

Phoenix

+1 (555) 922 3155

28883 Dora Hill

Phoenix

Phone

p +1 (555) 922 3155

Experience Experience

Detroit, MI

Scientist, Pharmacology

Detroit, MI

O'Conner, Schamberger and Ankunding

Detroit, MI

Scientist, Pharmacology

Provide leadership, develop research strategy, and coordinate pharmacology activities as the Pharmacology representative to drug discovery teams
Design and interpret pharmacology studies to evaluate the activities of drug candidates, investigate their mechanisms of action, and explore novel therapeutic hypotheses
Be responsible for communication between the drug discovery team and the pharmacology function and between R&D Leadership and drug the discovery team
Formulate data-driven decisions by designing and executing experiments that inform thinking and critical decision making for our program teams
Focus on developing and executing disease-relevant, in vitro and in vivo experiments to evaluate the efficacy and mode of action of novel drug candidates
Prepare, review and deliver scientific presentations for internal/external audience
Proven record of scientific achievements demonstrated by publications and presentations

San Francisco, CA

Senior Scientist, Pharmacology

San Francisco, CA

Kiehn-Hauck

San Francisco, CA

Senior Scientist, Pharmacology

Design and execute molecular imaging work plans supporting strategies for proof-of-target engagement and proof-of-biology of novel therapeutics
Optimize efficiency and productivity through effective management of work flow
Develop and execute novel in vitro assays to assess inhibition of viral, bacterial, or fungal growth by small molecules and/or biologics, and in vitro assays in support of vaccine development
Participates in discovery teams to provide expertise and knowledge from the pharmacology discipline. Helps identify relevant models and works within team to establish work plan for in vivo PK/PD and pharmacology support
Design and conduct in vivo studies in rodents to establish PK/PD relationships, and in vivo proof of concept for target validation in an immunology/inflammation-focused discovery environment
Establish and maintain a network of external collaborators (academic and industrial) and in the fields of pharmacology and biology
Represent Pharmacology on program teams and provide input on the design of the program’s research operating plan and strategy

present

Chicago, IL

Lead Scientist Pharmacology / Toxicology

Chicago, IL

Smith Group

present

Chicago, IL

Lead Scientist Pharmacology / Toxicology

present

Work with relevant managers to devise “fit-for-purpose” nonclinical plans and manage execution of strategy
Provide scientific and strategic leadership on new approaches to diagnostic imaging agent development in line with current guidance
Manage the tactical implementation of nonclinical studies (Work Statements, Protocols, Study Reports)
Work with other functions to produce fit for purpose documentation
Devise nonclinical development strategy according to relevant guidelines
Communicate strategy/progress updates to project team and key stakeholders
Attend external site visits for project meetings and to monitor key phases of studies

Education Education

Bachelor’s Degree in Biology

Cornell University

Bachelor’s Degree in Biology

Skills Skills

With notable publications and achievements within immunology
Maintain detail records of laboratory experiments using electronic laboratory notebook or paper records as necessary
Demonstrated knowledge or experience with characterization of immune cell populations in tumors by FACS is desired
Notable publications and achievements within immunology and/or cancer biology
Understands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner
Ability to independently design, conduct, interpret, and communicate results related to in vivo studies aimed at validating clinical leads in our pipeline
Possess in-depth knowledge in area
Expertise in drug discovery and development with protein-based therapeutics including monoclonal antibodies is highly desired
Experience with translational biology and/or early development of drug discovery programs is strongly desired
Able to critically analyze and interpret data

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Lead Scientist Pharmacology / Toxicology Resume Examples & Samples

Nonclinical/Biology expert on multiple cross-functional project teams
Devise nonclinical development strategy according to relevant guidelines
Communicate strategy/progress updates to project team and key stakeholders
Work with external partners (CROs and Academic Centres) to deliver high quality nonclinical data (Pharmacology, Pharmacokinetics, Toxicology, GLP or non-GLP) to support project progression
Manage Contract Research Organisations relationships and develop strategic partnerships as required. Develop good working relationships with external partners and leverage this to deliver high quality studies on time
Manage the tactical implementation of nonclinical studies (Work Statements, Protocols, Study Reports)
Attend external site visits for project meetings and to monitor key phases of studies
Preparation and review of nonclinical sections of key regulatory documentation
Work with other functions to produce fit for purpose documentation
Work with external experts to provide independent opinion/input and manage internal/external resources to complete required documentation on time
Provide scientific and strategic leadership on new approaches to diagnostic imaging agent development in line with current guidance
Be actively involved in guiding and supervising less experienced staff through theoretical understanding
Work with relevant managers to devise “fit-for-purpose” nonclinical plans and manage execution of strategy
As part of the Nonclinical Sciences team, this role will work closely with other stakeholders within and across functions (Regulatory Affairs, CMC, Clinical, Pharmacovigilance, External Alliances, Research Technology, Business Segment) and geographic locations to aid development of next generation imaging agents and support of product life cycle management
Represent the company on a purely scientific or scientific promotional level at external meetings
To co-author scientific papers for publication in refereed journals where appropriate
A degree in Biology, Biological Sciences, Pharmacology, Toxicology or a similar field
Experience in the Pharmaceutical industry
Experience of Product Safety Evaluation
Experience as a Lead Scientist, responsible for the biology/nonclinical component of research/development projects
PhD in a relevant field
Imaging experience
GLP (Good Laboratory Practice)

Senior Associate Scientist, Pharmacology Resume Examples & Samples

Design and conduct in vivo studies in rodents to establish PK/PD relationships, and in vivo proof of concept for target validation in a dynamic, fast-paced discovery environment
Directly enable the conduct of in vivo studies. Demonstrated expertise in small animal handling, dosing, recording of observations, blood and tissue collection and necropsy required
Communicate effectively within the Preclinical Sciences group, which includes colleagues in PK/bioanalysis
Experience in in vivo study conduct; animal handling, husbandry, dosing by multiple routes, observation recording, blood, tissue collection and limited necropsy
Ability to generate protocols, and record data in a notebook (electronic or hardcopy)
Knowledge of rodent models of immunology/inflammationStrong presence as well as sense of urgency and priorities as well as flexibility. The ability and strong desire to "make things happen"
Decisive as well as collaborative
High level of honesty and integrity
Excellent interpersonal skills with particular emphasis on communication & relationship building
Motivated to be part of an organization that aims to make a difference through cutting edge research
Passion for the pharmaceutical industry
LI-JW1

Senior Scientist, Molecular Pharmacology Resume Examples & Samples

Biochemistry assay development and screening
Mechanism of action studies
Molecular pharmacology DPT representation
Propose innovation
3 years of experience in a drug discovery environment
Background in biology
Experience in kinase, signaling

Pharmacology Associate Scientist Resume Examples & Samples

Drive data driven decisions by designing and executing experiments that inform thinking and critical decision making for our program teams
Focus on developing and executing in vivo disease-relevant assays to evaluate the efficacy and mode of action of novel drug candidates
Provide technical support with routine lab-based activities including; compound administration, and sample collection
Maintain active and timely records of experiments in appropriate databases and notebooks
Contribute to the interpretation and active dissemination of data
BS in pharmacology or a related biological discipline (e.g. cell biology, physiology, biotechnology or molecular biology)
Work experience in an academic or biopharmaceutical laboratory
Passion to drive science through hands on data generation
Laboratory experience in providing hands on technical support with in vivo experiments
Detail oriented self-starter, with strong abilities to problem solve and share ideas
Ability to work effectively in a team environment and accepting of coaching from others
Proficiency with Microsoft Word, Excel, and PowerPoint
Experience with data analysis, interpretation and presentation
Experience supporting in vivo drug metabolism or pharmacokinetic studies
Willingness to learn and master complex in vivo techniques
Laboratory experience with developing novel in vivo assays
Experience in one of the following areas of biology; cardiovascular, central nervous system, renal or respiratory

Scientist, Pharmacology Resume Examples & Samples

Provide leadership, develop research strategy, and coordinate pharmacology activities as the Pharmacology representative to drug discovery teams
Design and interpret pharmacology studies to evaluate the activities of drug candidates, investigate their mechanisms of action, and explore novel therapeutic hypotheses
Be responsible for communication between the drug discovery team and the pharmacology function and between R&D Leadership and drug the discovery team
Formulate data-driven decisions by designing and executing experiments that inform thinking and critical decision making for our program teams
Focus on developing and executing disease-relevant, in vitro and in vivo experiments to evaluate the efficacy and mode of action of novel drug candidates
Experience with a range of target / assay types including: biochemical, cell-based, histology/immunocytochemistry, PCR, ELISA,, and in vivo pharmacology procedures
Maintain active and timely records of experiments in appropriate databases and notebooks and contribute to the interpretation and active dissemination of data
Must be flexible, able to apply his / her knowledge to new areas of research, and thrive in a fast-paced team environment
Prepare, review and deliver scientific presentations for internal/external audience
Ph.D. in Pharmacology or a related biological discipline, or B.S./M.S. plus a minimum of 3 years of relevant industry experience
Extensive laboratory experience developing and conducting predictive in vitro and in vivo assays
Proven record of scientific achievements demonstrated by publications and presentations

Senior Scientist, Oncology Pharmacology Resume Examples & Samples

PhD in Immuno-Oncology with 3-5 years of industry or academic relevant experience in cancer immunology and in vivo pharmacology with track record of scientific publications and high level of proficiency with multi-color flow cytometry and mechanistic studies of immune regulation
Experience working with humanized mouse models is highly desirable
Good people organizational and presentation skills
Excellent interpersonal and team skills; track record of success working collaboratively

Senior Scientist Gpcr Mechanistic Pharmacology Resume Examples & Samples

Design and develop cellular model systems for functional profiling of biased ligands at multiple signaling events
Strong expertise in using plate based assays (fluorescence, luminescence, FRET, FP, high content imaging, label-free technologies, etc.) to characterize mechanism of drug action on GPCRs, enzymes, or ion channels drug targets at the functional, phenotypic, or biochemical level
Strong theoretical and practical knowledge of GPCR receptor pharmacology
Highly effective written and verbal communication skills
Ability to identify, learn and creatively apply new technologies to improve efficiency and data quality
Must be flexible to learn and take on new tasks according to shift in priority
Ability to multi-task, and independently design, execute experiments and communicate results to team members
Collaborative, well-organized, with the ability to take the initiative to lead, influence and motivate others
Must have a lot of passion and experience working with lab automation and applying new technologies into the drug discovery process
Strong problem solving and communication skills
A Ph.D in pharmacology, neurology, cell biology, biochemistry or a related discipline with 5+ years of assay development and execution experience in the biotechnology/pharmaceutical industry, or a M.Sc. with 15+ years of equivalent experience, is required

Scientist, Pharmacology Resume Examples & Samples

Ph.D. in immunology and preferably focused on tumor immunology
8+ years of direct experience working with the pharmaceutical or biotechnology industry
Expertise in immunology
Competent with multiple in vivo approaches to elucidate the mechanisms of drugs aimed at modulation of the immune system
Experience with mouse models of oncology including subcutaneous and orthotopic xenografts, syngeneic, and leukemia models
With notable publications and achievements within immunology
Ability to independently design, conduct, interpret, and communicate results related to in vivo studies aimed at validating clinical leads in our pipeline
Direct experience working with the pharmaceutical or biotechnology industry
Must have experience with flow cytometry. Demonstrated experience with characterization of immune cell populations in tumors by FACS is desired
Must have strong written and verbal communication skills, with the ability to clearly articulate complex concepts and strategies
Must have demonstrated leadership and critical thinking skills
Expertise in drug discovery and development with protein-based therapeutics including monoclonal antibodies is highly desired
Experience with translational biology and/or early development of drug discovery programs is strongly desired

Senior Scientist, Cellular Pharmacology Resume Examples & Samples

Independently design and implement various cellular in vitro assays using a wide range of methodologies
Execute semi- and fully automated high throughput compound and biologics screens in support of internal drug discovery programs
Develop and execute experimental strategies to define biomarkers, mechanisms of action and resistance of therapeutic agents of interest
Properly document and report the experimental findings and provide scientific contribution to research projects/programs in multiple disease areas
Work closely with members within department and across functional teams in support of research projects/programs at different stages
Extensive job related laboratory research experience and medium/high throughput assay execution in academic or industrial setting
Hands-on assay development and troubleshooting skills and proficiency with different high throughput screen formats
Solid data analytical and problem solving skills and proficiency in standard scientific software used for data analysis
Excellent oral and written communication skills, including preparation of study reports, presentations and manuscripts for publication in peer reviewed scientific journals
Demonstrated ability to function and communicate effectively in a multi-disciplinary environment and thrive in a team environment

Senior Scientist, Pharmacology Resume Examples & Samples

Develop and execute novel in vitro assays to assess inhibition of viral, bacterial, or fungal growth by small molecules and/or biologics, and in vitro assays in support of vaccine development
Validate and integrate new technologies or methodologies, as needed, to address questions related to drug discovery programs and projects
Optimize efficiency and productivity through effective management of work flow
Evaluate outsourcing options and design work plans as appropriate
Represent Pharmacology on program teams and provide input on the design of the program’s research operating plan and strategy
Ensure timely communication and delivery of high-quality in vitro data to Therapeutic Area program teams
Ability to understand and implement applicable regulations regarding the use of pathogens (e.g. virus, bacteria, fungi), human cell and tissue use, laboratory safety, health physics and chemical hazards in research
Experience in the design, development and execution of in vitro assays for anti-infective drug development programs targeting antivirals, antibacterials, antifungals, and/or vaccines
Strong collaborative skills
Skill in troubleshooting experimental design, assay development and data analysis
Experience in assay development in support of antibacterial, antifungal drug discovery

Scientist, / II Pharmacology Resume Examples & Samples

Perform routine tissue sectioning using paraffin embedded blocks and frozen tissues
Perform histological staining including H&E staining, immunohistochemistry, immunofluorescence staining, etc
Perform microscopy analysis using bright field, fluorescent as well as confocal microscope
Perform image capture, quantification and data analysis
Manage tissue samples, blocks, slides as well as image inventories
Identify, develop, and optimize new methods to generate reliable and reproducible data in a timely manner
Independently execute designed experiment plans and interpret study observations
Effectively and accurately record and report experiment results
Troubleshoot effectively and think proactively
Bachelors or Master degree in biology, pharmacology, pathology or related fields
A minimum of 3 - 5 years of relevant laboratory experience in an academic or biotech/pharmaceutical industry setting
Knowledge and experience with histological process
Experience with microscopy and image analysis
Excellent material and data managing and organizing abilities
Excellent learning abilities
Experience with brain histology, immunohistochemistry and imaging is highly preferred
Experience with molecular and cell based assay is a plus

Senior Scientist, Pharmacology Resume Examples & Samples

Design and conduct in vivo studies in rodents to establish PK/PD relationships, and in vivo proof of concept for target validation in an immunology/inflammation-focused discovery environment
Identify CROs or other collaborations that could enable models or apply expertise that is not available in-house. Collaborate, monitor and report CRO based studies to discovery project teams
Directly enable the conduct of in vivo studies, as well as the ability to supervise/mentor other scientists/associates in the pharmacology group
Data collection in electronic notebook or in hardcopy laboratory notebooks is critical
Serve as a Principal Investigator on IACUC protocols. Able to draft protocols and present clearly to IACUC committee
Participates in discovery teams to provide expertise and knowledge from the pharmacology discipline. Helps identify relevant models and works within team to establish work plan for in vivo PK/PD and pharmacology support
Communicate effectively within group to establish clear priorities and seek alignment on a work plan that meets discovery team needs
Collaborate with pharmacology group at other Celgene sites to assure that best practices are used to evaluate targets in discovery from an in vivo perspective
Solid understand of immunology discovery research, focused primarily on in vivo and ex vivo evaluations of small molecules targeted to immune/inflammatory disease targets
Ability to provide expertise and guidance to discovery project teams with regard to animal models of disease and relevant PK/PD and biomarker assessments. Knowledge of the literature and current science in pharmacology assessments
Ability to generate high quality data in a dynamic high paced environment
Knowledge of outsourcing CROs and monitoring of studies at outsourced sites
Knowledge of in vitro assessment of pharmacologic activity

Scientist, Cancer Pharmacology Resume Examples & Samples

Independently design and execute studies to assess activity of biotherapeutics in xenograft and syngeneic mouse tumor models
Develop, advocate, and execute lead optimization and translational strategies
Independently analyze, interpret data, and present data in internal (lab meetings, journal clubs; leadership meetings) and external settings (collaborator meetings, conferences)
Maintain accurate, complete, and timely data in laboratory notebooks
Ph.D. with a strong publication record in peer-reviewed journals
Experience with oncology biotherapeutics, and a strong track record of scientific and drug discovery achievement
The position requires broad knowledge of oncology biology and in vivo pharmacology, including model selection and development, PK/PD/E studies, and drug combination strategies
Strong organization, interpersonal, and communication skills (oral and writing) are essential
Entrepreneurial and innovative perspective on drug discovery with the ability to translate concepts into action

Associate Principal Scientist, Pharmacology Resume Examples & Samples

Conceptualize, design and develop biochemical and biophysical assays for high throughput screening and follow up characterization of hit classes of interest. The characterization should shed light on the mechanism of compound action on the target to enable medicinal chemistry design for lead identification and optimization
Manage a portfolio of programs, create and implement hit finding plans and coordinate workflows and logistics within and across departments to meet project goals and milestones
Champion new technologies and capabilities within the Biophysics group and provide coaching and leadership from the laboratory
Participate in multidisciplinary teams and facilitate collaborations internally and externally
3 years of relevant postdoctoral/industry experience, biophysics expertise
In depth knowledge of biophysics with experience in SPR technology and its application in mechanism of action studies are essential
Strong communication and collaborative skills with an ability to influence and impact at a strategic level
Demonstrated solid track record of scientific achievements and scientific mentoring/management experience

Associate Principal Scientist Pharmacology Resume Examples & Samples

Experience using preclinical models to evaluate the pharmacology of novel cancer drugs
A minimum of 3 years of post-doctoral experience; at least 2 years industry experience is preferred
Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps
Proven skills in leading small scientific teams

Scientist, Pharmacology Resume Examples & Samples

Develop general molecular biology tools, vectors and protocols geared towards advancing drug discovery activities
Support next-generation sequencing characterization of proprietary in vitro and in vivo oncology models including, but not limited to, whole genome bisulfite sequencing and single cell RNA-Seq
Perform genetic and pharmacologic validation of genetic/epigenetic targets using advanced molecular and cell biology assays
Critically analyze and report/communicate data with the intent of informing colleagues and drafting innovative solutions
Next-generation sequencing methods including library preparation
Single cell strand specific qRT-PCR
Flow cytometry and alternative protein quantitation methods
Lentiviral shRNA and CRISPR knockdown/knockout technologies applied to patient-derived xenografts (PDXs) and 3D organoid mammalian cultures
Transgenic cell line creation
Able to design complex experiments with scientific rationale
Able to critically analyze and interpret data
Learning the drug development process
Draw appropriate conclusions
Possess in-depth knowledge in area
Understands fundamental scientific problems and can apply knowledge to research and development projects and problems in a positive manner
Developing skills in critical interpretation of scientific data and problem solving and reporting of scientific data
Contributes individually as well as on cross functional teams
Responsible for more complex assignments and for more than 1 project
Able to evaluate CRO's
Well versed in fundamentals of functional area
Understands the context, impact and timely communication of data

PhD Scientist, Molecular Pharmacology Resume Examples & Samples

Strong records of publication in peer-reviewed scientific journals
Proven record as driver for scientific innovation
Experience with imaging, liquid handling and automation platforms a plus
Knowledge in Oncology including cell signaling, cell cycle and apoptotic pathways
Detail-oriented, self-motivated and scientifically driven, proficient reasoning skills in experimental design, data analysis and interpretation
Excellent communication, presentation and interpersonal skills

Senior Scientist, Pharmacology Resume Examples & Samples

Design and execute molecular imaging work plans supporting strategies for proof-of-target engagement and proof-of-biology of novel therapeutics
Ensure high quality experimental design and interpretation of projects involving molecular imaging in research and early development
Establish and maintain a network of external collaborators (academic and industrial) and in the fields of pharmacology and biology

Senior Scientist, Cellular Pharmacology Resume Examples & Samples

Design and execution of experimental strategies for target and pathway validation
Implementation and validation of various cellular in vitro and ex vivo assays using a wide range of methodologies
Cell line generation utilizing state-of-the art genetic manipulations and gene knock-down techniques
Establishment of primary cell cultures, including 3D and co-cultures from different organs
Proper documentation and reporting of the experimental findings and scientific contributions to research projects/programs in multiple disease areas
Effective collaboration with members within department and across functional teams in support of research projects/programs at different stages
Extensive job related laboratory research experience with tissue culture, cell line generation and cellular assay execution in academic or industrial setting
Hands-on cellular assay development and troubleshooting skills, and proficiency with different cellular screening formats
Excellent oral and written communication skills, including preparation of study reports, presentations and manuscripts for publication in peer-reviewed scientific journals
Proven ability to function and communicate effectively in a multi-disciplinary environment and thrive in a team environment

Pharmacology Scientist Novartis Institute for Tropical Diseases Resume Examples & Samples

Independently design, troubleshoot, develop and implement animal models for tropical infectious diseases to characterize in vivo the pharmacological properties of anti-parasitic small molecule inhibitors
Collaborate with disease biology experts to develop innovative pharmacodynamics readouts and characterize mechanisms of resistance and action of potential new drugs
Ensure best practices in data analysis by ensuring integrity and quality of data in a timely manner
Be self-driven and able to contribute significantly on hypothesis, experimental design, interpreting primary pharmacological data, providing expert input, communicating results and report writing
Execute smooth running of in vivo assays by liaising with key stakeholder
Mentor junior research associates
Comply with Novartis standards and practices for documenting and archiving research activities
Maintain compliance with local and global standards in Health/Safety & Environment
Keen interest and demonstrated experience in the field of anti-infective / chemotherapeutics. Specific knowledge or expertise in working with Plasmodium, kinetoplastics or Cyrptosporidium animal models will be an advantage
Knowledge in pharmacokinetics and pharmacodynamics concepts and data analysis is a plus

Scientist, M&S, Quantitative Pharmacology Resume Examples & Samples

Develop and execute quantitative strategies in collaboration with the cross functional development project teams to include Clinical Pharmacology, Biostatistics, Clinical Sciences, and Regulatory Affairs
Using population based modeling methodologies develop exploratory Pop PK and PK/PD models to aid in research and development programs spanning early non-clinical pharmacology efforts through clinical phase 3 dose-selection and dose justification
Develop population PK and PK/PD covariate models to support global regulatory activities and market access applications
Develop mechanistic, exposure-response and disease models to support on-going clinical development programs from early clinical development through market application and post-marketing commitments
Establish and execute a variety of non-population based quantitative pharmacology analyses as appropriate to best address the needs of an on-going development program
Work with colleagues within Clinical Pharmacology, Preclinical PK, Toxicology and Early Clinical Development to provide appropriate quantitative pharmacology support for FIH dose selection and study design
Provide technical and subject matter expertise to the clinical project team on matters relating to quantitative pharmacology
Expand the Quantitative Pharmacology and modeling & simulation capability through evaluation, implementation, and publication of new data analysis techniques, software, computational infrastructure, personal technical skill, as well as the strategic application of quantitative pharmacology and population based M&S methodologies across the development portfolio
Work cooperatively and synergistically with the other members in the Quantitative Pharmacology function and across the organization

Scientist, Pharmacology Resume Examples & Samples

Bio Analytic / Drug Metabolism Pharmacokinetics
Immunoassays
ELISA
Mesoscale/ECL
QPCR or FACS

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