Scientist, Immuno Resume Samples

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MO
M O'Connell
Merritt
O'Connell
355 Jones Corner
Detroit
MI
+1 (555) 156 9025
355 Jones Corner
Detroit
MI
Phone
p +1 (555) 156 9025
Experience Experience
Philadelphia, PA
Scientist, Immuno
Philadelphia, PA
Emmerich and Sons
Philadelphia, PA
Scientist, Immuno
  • Manage internal projects in immuno-oncology drug development
  • Work closely with corporate partners to support preclinical, translational and clinical development of cancer therapeutics
  • Independently design, conduct, interpret and report in vitro studies using a wide range of established methodologies
  • Work with external academic, biotechnology, and contract research organizations
  • Develop and deliver scientific presentations and reports
  • Represent programs and science to senior management
  • Independently design, plan, execute and interpret complex in vivo studies focused on identifying drug candidates within the areas of immune-oncology
Los Angeles, CA
Senior Scientist, Immuno
Los Angeles, CA
Jakubowski-Reichert
Los Angeles, CA
Senior Scientist, Immuno
  • Develop, maintain, and train colleagues on both established and novel innovative in vivo/ex vivo assays/analyses of immune and tumor cell population
  • Design and execute experiments, critically interpret data and provide future directions
  • Work across multiple groups to develop and evaluate antibody or cell based therapeutics in oncology indications and drive their preclinical evaluation
  • Effectively record and report experiments; make project presentations
  • Develop compelling scientific presentations and reports for internal review meetings and external scientific conferences/journals
  • Develop assays and models for efficacy testing and lead selection of immuno-oncology approaches and combination therapies
  • Establish and apply in vitro, in vivo, and ex vivo assays and models to identify and characterize novel therapeutics
present
Los Angeles, CA
Senior Scientist, Immuno Biologics
Los Angeles, CA
Parker, Sawayn and Gorczany
present
Los Angeles, CA
Senior Scientist, Immuno Biologics
present
  • Designs and develops tumor biology models, immune-oncology related models and translational research to understand mechanism of action responsible for preclinical efficacy for cancer and immunotherapy applications
  • Support drug discovery programs by providing relevant scientific and strategic input to project teams regarding relevant biomarkers and pharmacodynamics models
  • Design, execute and validate a variety of assays to understand target of interest and characterize different biologic therapeutic prototypes for IO applications
  • Develop and conduct in vitro and ex vivo mechanism of action studies to support data for efficacy studies
  • Function effectively as a part of both functional and cross functional teams by interfacing with project teams to meet timelines and blueprints for target product profile
  • Troubleshoot complex problems in creative and effective ways; whenever necessary and actively participates in innovation and/or optimization of established processes to ensure project goals are met
  • Spends 90% time in the laboratory, including hands on mentoring of scientists
Education Education
Bachelor’s Degree in Immunology
Bachelor’s Degree in Immunology
The University of Kansas
Bachelor’s Degree in Immunology
Skills Skills
  • Computer skills: detailed knowledge of Excel, Word, Powerpoint and Graphpad prism
  • Proven track record of good experimental design, in-depth data analysis and interpretation based on strong scientific rationale
  • Strong experience in protein expression using HEK293 and CHO cells
  • Hands on experience with various in vivo/ex vivo immunology-related assays (such as human/mouse T cell differentiation and in vitro derivation of various immune cell subsets from human and mouse sources)
  • Ph.D. in Immunology or Oncology, with a strong publication record in peer-reviewed journals
  • Provide in-depth expertise and hands-on experience in developing mouse and human cell-based functional immunological assays, including flow cytometry and ELISA based assays
  • Team player with strong interpersonal skills and high ethical standard
  • Demonstrated ability to write scientific reports and publications
  • Good oral and written communication skills
  • Ability to work in a creative and fast-paced culture and productive team environment
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15 Scientist, Immuno resume templates

1

Research Scientist, Immuno Resume Examples & Samples

  • Utilize knowledge of relevant scientific and clinical literature to aid development of testable, innovative hypothesis for cancer immunotherapy
  • Independently design and execute in-vitro, ex-vivo, and in-vivo studies focused on immunotherapy – both internally and through external partners (CROs and collaborators)
  • Interpret data, discuss conclusions and present at various internal and external forums
  • Strong publication record in the areas of immunology or cancer biology
  • Experience with developing and conducting T-cell functional assays is a plus
  • Experience with immunocompetent mouse tumor models and ex-vivo immune functional analyses including multi-color FACS is a plus
  • Ability to work in a fast-paced and highly collaborative environment
2

Senior Scientist, Immuno Resume Examples & Samples

  • Conceive and execute novel multi-disciplinary immuno-oncology research strategies in the area of innate immunity that encompass late stage and early stage discovery programs
  • Interact with cross-functional teams to establish productive collaborations within and outside of AbbVie
  • Develop, maintain, and train colleagues on both established and novel innovative in vivo/ex vivo assays/analyses of immune and tumor cell population
  • Make strong contributions to research team short- and long-term scientific strategies
  • Develop compelling scientific presentations and reports for internal review meetings and external scientific conferences/journals
3

Senior Scientist, Immuno Resume Examples & Samples

  • Drive innovation through a deep understanding of the immunology field and the application of new technologies and methods
  • Develop and deliver scientific presentations and reports
  • PhD; MS; BS in Immunology, Biology, Biochemistry or related field with 3+ years (PhD); 10+ years (MS); or 12+ years (BS) of relevant immunology research experience with an oncology focus in academia and/or the pharmaceutical industry
  • Proficiency in a wide range of immunological laboratory techniques
  • Experience with biologic therapeutics
  • Ability to communicate scientific concepts and strategies effectively in a science setting
4

Scientist, Immuno Resume Examples & Samples

  • Independently design, plan, execute and interpret complex in vivo studies focused on identifying drug candidates within the areas of immune-oncology
  • Formulation of small molecules for in vivo studies
  • Evaluation of pathway biomarkers, immunoprofiling and endpoints from in vivo studies via techniques such as flow cytometry, qPCR, IHC, ELISA, Mesoscale and Western blots
  • Plan, execute and interpret pharmacokinetic/pharmacodynamic studies in acute and chronic disease models
  • Data presentation to multidisciplinary discovery teams
  • Participate in the evaluation of new targets
  • Preparation of technical reports
  • Represent department on discovery teams, participating at the level of the core team
  • Additional responsibilities include representation of the department on discovery teams, sub-teams and in target identification discussions
  • The candidate will be expected to lead by example and provide training, supervision and mentorship to junior scientists
  • Ph.D. degree in immunology, tumor biology or pharmacology with at least 3 years of successful post-doctoral experience, evidenced by a strong publication record, plus a minimum of 2 years of successful experience in immuno-oncology as a bench scientist in the biotechnology or pharmaceutical industry setting
  • Must be a broadly experienced in vivo pharmacologist in the areas of immuno-oncology that demonstrates good communication skills, is highly flexible, results-oriented, who enjoys working in a fast-paced environment
  • Proven track record in validating and implementing animal models of immuno-oncology and oncology for the development of small and large molecules
  • Relevant knowledge and experience in humanized mouse models in oncology
  • Advanced knowledge of FACS
  • Proven track record in developing and validating PDX models of liquid tumors (AML, MDS) and other solid tumors
  • Relevant skills include proficiency in in vivo modeling of oncology and immunological technique, eg flow cytometry, intracellular staining, cytotoxicity assays, cytokine analysis etc
  • Proficiency in isolation and characterization of immune cells from tumors and other tissues
  • Proven track record of good experimental design, in-depth data analysis and interpretation based on strong scientific rationale
  • Able to problem solve and offer potential solutions
  • Works independently or as part of a team
  • Computer skills: detailed knowledge of Excel, Word, Powerpoint and Graphpad prism
5

Scientist, Immuno Resume Examples & Samples

  • Maintain in-depth knowledge of fundamentals of immunology, immune oncology, and tumor biology
  • Collaborate with scientific staff in design and execution of experiments to evaluate immune oncology drug candidates including drug candidate screening, lead optimization, mechanism of action, preclinical proof of concept studies, biomarker development and translational studies
  • Manage internal projects in immuno-oncology drug development
  • Serve on internal project teams and committees as scientific functional lead
  • Work closely with corporate partners to support preclinical, translational and clinical development of cancer therapeutics
  • Ph.D. degree in immunology, tumor biology or cellular biology with at least 3 years of successful post-doctoral experience, evidenced by a strong publication record, plus a minimum of 2 years of successful experience as a bench scientist preferably in the biotechnology or pharmaceutical industry setting
  • A deep understanding of both human and murine myeloid biology pertaining to maturation, signaling pathways and functional of tissue-resident macrophages and antigen presenting cells and/or knowledge of tumor microenvironment and its impact on the immune system
  • Extensive experience performing primary immune cell assays using human myeloid cells and understanding immune pathways impacted by myeloid cell function
  • Relevant skills include proficiency in cell biology and immunological technique, eg flow cytometry, intracellular staining, cytotoxicity assays, cytokine analysis etc
  • Effective team building and teamwork skills and ability to interact with and manage research scientists, project teams, outside collaborators and commercial vendors. Prior experience in working across R&D sites is preferred
  • Detail-oriented with the ability to identify and implement creative solutions
  • Ability to prioritize and manage time efficiently, Understanding of the research process, validation, and regulations that apply to clinical investigations and laboratory studies that support regulatory submissions is desirable
6

Scientist, Immuno Resume Examples & Samples

  • Perform PCR reactions, molecular cloning, plasmid DNA generation and characterization
  • Transient mammalian cell expression (using HEK293 and CHO cells) including DNA preparation, transfection and cell culture
  • Independently execute designed experiment plans, troubleshoot effectively and interpret study observations
  • Effectively record and report experiments and present results at various internal meetings
  • Proactively interact and effectively collaborate with team members from multiple functional areas on complex projects
  • Ph.D. degree in molecular biology, biochemistry or related field with at least 2 years of relevant laboratory experience in an academic or biotech/pharmaceutical industry setting; or Master degree in molecular biology, biochemistry or related field with at least 6 years of relevant laboratory experience in an academic or biotech/pharmaceutical industry setting; or Bachelor degree in immunology or related field with at least 10 years of relevant laboratory experience in biotech/pharmaceutical industry setting
  • Experience in antibody structure-functions, protein design and expression
  • Significant experience in leading or involving engineering of therapeutic bispecific antibodies
  • Strong experience in protein expression using HEK293 and CHO cells
  • Candidates with experience with engineering of T-cell redirected bispecific antibodies and other immunomodulatory antibodies will be given preferential consideration
  • Candidates with extensive experience on antibody engineering using with phage display and/or yeast display will also be given preferential consideration
  • Well-organized, self-directed and self-motivated with “can-do” attitude
  • Demonstrated ability to write scientific reports and publications
  • Team player with strong interpersonal skills and high ethical standard
7

Senior Scientist, Immuno Resume Examples & Samples

  • Contribute to antibody engineering efforts using emerging technologies for humanization, lead optimization, and multi-specific engineering
  • Design peptide, protein and antibody engineering strategies for lead optimization
  • Perform peptide, protein and antibody mutagenesis libraries for lead optimization using screening and/or selection methods
  • Perform peptide, protein and antibody mutagenesis libraries screening and selection
  • Perform phage and /or yeast library generation, selection, screening and analysis of the variant molecules
  • Protein purification using affinity, ion change and size exclusion column chromatography
  • Protein characterization using SDS-PAGE, Western blots, ELISA, FACS and other biochemical assays
  • Design and independently execute experiment plans and interpret study observations; Troubleshoot effectively
  • Effectively record and report experiments; make project presentations
  • Proactively interact and effectively collaborate with team members from cross-functions on complex projects
  • Abreast of current literature and development trends of immunomodulatory antibodies
  • Strong knowledge and experience protein or antibody engineering, expression construct construction, mammalian cell expression and purification, biochemical, biophysical and in vitro biological characterization
  • Significant hands-on experience with bispecific antibody engineering, expression, purification and characterization
  • Candidates with extensive experience on antibody engineering using with phage display and/or yeast display will be given preferential consideration
  • Ability to work in a creative and fast-paced culture and productive team environment
8

Scientist, Immuno Resume Examples & Samples

  • Provide in-depth expertise and hands-on experience in developing mouse and human cell-based functional immunological assays, including flow cytometry and ELISA based assays
  • Identify and validate novel immuno-oncology therapeutic targets and pathways
  • Establish assays and identify biomarkers to elucidate mechanism of action of drug candidates
  • Explore drug resistance and potential combination strategies for immuno-oncology therapeutics
  • Bachelor's or Master's degree in Biology or related field of study
  • 3+ years of relevant immunology experience in academia or industry
  • A rigorous, detail-oriented, team-based work habit
  • Direct experience developing mouse and human cell-based assays using a variety of immunological endpoints
  • Hands-on multi-color flow cytometry experience
  • Outstanding oral presentation and written communication skills
  • Strong background in immunology and cancer biology
  • Familiarity with multiple assay platforms/screening technologies ex. MSD, Luminex
  • Drug discovery experience
9

Senior Scientist / Scientist, Immuno Resume Examples & Samples

  • Work with various pre-clinical models of xenograft/syngeneic mouse tumor models, including the use of genetically modified mouse strains and humanized mouse models
  • Develop and advocate translational hypotheses and strategies for immuno-oncology projects
  • Able to present data in a succinct fashion in various internal (lab meetings, journal clubs; leadership meetings) and external settings (collaborator meetings, conferences)
  • Ph.D. in Immunology or Oncology, with a strong publication record in peer-reviewed journals
10

Senior Scientist, Immuno Biologics Resume Examples & Samples

  • Designs and develops tumor biology models, immune-oncology related models and translational research to understand mechanism of action responsible for preclinical efficacy for cancer and immunotherapy applications
  • Support drug discovery programs by providing relevant scientific and strategic input to project teams regarding relevant biomarkers and pharmacodynamics models
  • Design, execute and validate a variety of assays to understand target of interest and characterize different biologic therapeutic prototypes for IO applications
  • Develop and conduct in vitro and ex vivo mechanism of action studies to support data for efficacy studies
  • Troubleshoot complex problems in creative and effective ways; whenever necessary and actively participates in innovation and/or optimization of established processes to ensure project goals are met
  • Spends 90% time in the laboratory, including hands on mentoring of scientists
  • Supervises 1-2 junior scientists in Immuno Biologics focusing on pharmacology and cellular assays
  • May lead discovery projects
  • PhD in Immunology with a minimum of 7+ years of relevant experience, preferably in industry
  • Publications in peer reviewed journals demonstrating achievement in the above
  • Extensive hands-on experience and knowledge in a wide range of immunological assays using primary immune cells including T cells, Macrophages and dendritic cells to design new approaches for tumor killing mechanisms
  • Hands –on experience and ability to work with minimum supervision in carrying out high throughput data acquisition, analysis, storage and reporting by FACS CANTO, FACS ARIA, ELISA, Luminex, and other flow based cytokine assays is required
  • Experience with mammalian cell culture with best practices in tissue culture is required
  • Experience working with various mouse models for immunotherapy applications is required
  • Experience with primary human cells and tissues is strongly desired
  • Self-motivated, collaborative with excellent time management and organizational skills
11

Senior Scientist, Immuno Resume Examples & Samples

  • Candidate should have experience in primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques/platforms (e.g. Western, ELISA, Mesoscale), as well as RT-PCR
  • Candidate should be competent in standard scientific software used for data analysis (e.g. Microsoft Excel) as well as Microsoft Word and PowerPoint
  • Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps
  • Candidate must have expertise in developing in vitro and in vivo assays to investigate immune function and possess a deep knowledge of technologies commonly used to assess immune endpoints
12

Scientist, Immuno Resume Examples & Samples

  • Independently design, conduct, interpret and report in vitro studies using a wide range of established methodologies
  • Contribute scientifically to drug discovery research programs, including identification and validation of novel targets
  • Collaborate with members from other functional areas, including medicinal chemistry, biologics, in vivo and in vitro pharmacology and translational sciences
  • Candidate should be competent in standard scientific software used for data analysis (e.g. Microsoft Excel, Microsoft Word and PowerPoint)
  • Proven record of innovative thinking to propose and champion new ideas and solve problems
13

Scientist, Immuno Resume Examples & Samples

  • Independently design and execute studies to assess immunological impact of oncology-related therapeutic agents on primary immune cells
  • Independently analyze and interpret data, including FACs data
  • Experience with immune profiling in the context of tumorigenesis, and hands-on experience with mouse tumor models is essential. Experience in drug discovery is preferred but not essential
  • Hands on experience with various in vivo/ex vivo immunology-related assays (such as human/mouse T cell differentiation and in vitro derivation of various immune cell subsets from human and mouse sources)
14

Principal Scientist, Immuno Oncology Resume Examples & Samples

  • In-depth knowledge of fundamentals of immunology, immune oncology, and tumor biology in solid and hematological malignancies
  • Knowledge of biomarker discovery and development: assay development/validation, clinical discovery of biomarkers, MoA research, knowledge of platforms
  • Supervise scientific and technical staff
  • Understand the context, impact and timely communication of data
  • Ph.D. degree in immunology, tumor biology or cellular biology, or pharmacology with at least 3 years of successful post-doctoral experience, evidenced by a strong publication record, plus a minimum of 8 years of successful experience as a scientist preferably in the biotechnology or pharmaceutical industry setting
  • Expertise in developing biomarkers for clinical trials, and strong knowledge in immunology and tumor biology, knowledge of hematopoietic malignancies desired
  • Relevant skills include proficiency in immunological techniques (flow cytometry, intracellular staining, cytotoxicity assays, ELISA, ELISpot, etc.), cell biology (transient and stable engineering of cell lines, also using viral transduction, immunocytochemistry, microscopy), and molecular biology (molecular cloning, transient and stable gene silencing, methylation specific PCR) techniques
  • Familiarity with data management tools and software for analyzing translational data sets from various assay formats. Biological interpretation of high content data sets in collaboration with computational biology
15

Senior Scientist, Immuno Resume Examples & Samples

  • Guide and implement the strategy and planning for the prospective identification and validation of immuno-oncology targets
  • Develop assays and models for efficacy testing and lead selection of immuno-oncology approaches and combination therapies
  • Work across multiple groups to develop and evaluate antibody or cell based therapeutics in oncology indications and drive their preclinical evaluation
  • Design and execute experiments, critically interpret data and provide future directions
  • PhD or MS in Immunology, Biology, Biochemistry or related field with 5+ years (PhD); 8+ years (MS) of relevant immunology research experience with an oncology focus in academia and/or the pharmaceutical industry
  • Proficient in T-cell culture, flow cytometric methods, cell-based in vitro functional assays with immunocompetent cells (adaptive and innate)
  • Hands-on experience isolating immune cells from human and animal tissue including tumor infiltrating cells
  • Experience developing new methods and establishing assays, with a preference for antibody and cell-based techniques
  • Experience with setting up syn- and xenogeneic in vivo models for the evaluation of cell based and antibody therapeutics
  • Experience with generating and handling engineered T-cells is highly preferred
  • Ability to multitask and manage multiple projects simultaneously, keep up-to-date with relevant literature, meet frequently tight deadlines and work independently, while effectively interacting and communicating with other scientists and teams
16

Associate Scientist, Immuno Resume Examples & Samples

  • Design, perform and interpret complex in vitro and ex vivo experiments
  • S/he must demonstrate the ability to analyze and present data in professional 'publication ready' format
  • S/he will work independently and manage multiple experiments simultaneously
  • S/he will contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions, keep up-to-date with the literature related to his/her field, and be able to demonstrate clear and professional verbal and written communication
  • B.S. /B.A. with at least 2 years of experience OR a M.S. with at least 1 year of experience is required
  • Strong cell biology and assay development skills are required
  • Previous experience analyzing immune compartments/responses in presence of therapeutics is preferred
  • A background in cancer biology or immunology is preferred
  • MSD, multi-color flow cytometry and cell culture experience is required
  • Proficiency in cellular immunologic assays, including the assessment of proliferation, activation and cytokine production in T cell and PBMC functional assays is preferredR&D
17

Senior Scientist, Immuno Biologics Resume Examples & Samples

  • Independently performs and evaluates experiments from conception through data interpretation
  • Evaluates, designs and helps execute collaborations with external partners (academic / industry)
  • Partners with translational medicine and early clinical teams to propose and validate biomarker strategies for clinical proof-of-mechanism
  • Spends up to 90% of time in laboratory, including hands-on mentoring of scientists
  • Presents results both written and verbal and delivers completed reports within a multidisciplinary team environment
  • Complies with laboratory safety procedures
  • Ph.D. in Immunology and/or Molecular Biology with 4+ years of relevant experience or MS/MA with 14+ years of relevant experience or BS/BA with 16+ years of relevant experience
  • Experience with Immunology research is necessary
  • Experience with gastrointestinal biology and/or pathology is preferred
  • Minimum 5 years Industry experience in advancing Biologics programs
  • Experience in cross-mentoring talent in a matrix environment
18

Senior Scientist, Immuno Resume Examples & Samples

  • This individual should have deep technical experience in immunology and oncology research with preferred experience in T cell biology including T cell receptors
  • This individual will be responsible for generating antigen-specific T cell clones, identifying and characterizing T cell receptors and functional biology
  • This person will ensure scientific excellence, quality and completeness of key platform initiatives
  • Ph.D. in Immunology or related major with typically 2-5 years of experience. Preference for some industry experience
  • Demonstrated excellence and productivity in independent research
  • Extensive knowledge of T cell biology research
  • Level commensurate with experience
  • Practical experience with primary cell culture, T cell based assays, and molecular biology techniques is required
  • Additionally a strong expertise in molecular biology, T cell biology and oncology research experience is desirable
  • Skills include, but not limited to: flow cytometry (FACs), PCR, qPCR, ELISA, Luminex, retroviral/lentiviral based transduction systems, T cell clone generation
19

Scientist Immuno Resume Examples & Samples

  • Doctorate degree in pharmaceutical, chemical, or biological science
  • Two years’ experience in translational/clinical assay development pertaining to immuno-oncology
  • A strong background in tumor biology and cancer genomics
  • The successful candidate must display a strong entrepreneurial spirit, in line with Amgen’s culture of innovation and pursuit of scientific excellence
20

BS / MS Scientist, Immuno Resume Examples & Samples

  • Design and develop a broad range of cell based functional and phenotypic assays for characterization of myeloid cells and T cells to accelerate projects in pre-clinical and clinical development
  • Conduct in vitro mechanism of action studies using primary human or mouse immune cells and cell lines to evaluate activity of candidate therapies
  • Design and execute experiments independently; accurately record, analyze and communicate data to senior staff and team members
  • Present results in team meetings and deliver presentations to both small and large groups
21

Principal Scientist, Immuno Resume Examples & Samples

  • Generate biological hypotheses (e.g., patient selection, drug combinations, new targets) in various oncology (and non-oncology) disease areas arising from interpretation of Molecular Medicine data
  • Implement the Molecular Medicine platform by facilitating research collaborations, contracting, experimental design, experimental execution and data analysis
  • Collaborate with Molecular Medicine computational and system biology team members to provide scientific input to their in silico disease modeling efforts