Scientist, Immuno Job Description
Scientist, immuno
provides scientific expertise in the areas of immunology, cancer biology and molecular genetics (especially in breast cancer, prostate cancer, colon cancer, and immune-oncology), next generation sequencing and polymerase chain reaction theory and methods, and tissue- and non-tissue-based methods for evaluating tumor-associated biology.
Scientist, Immuno Duties & Responsibilities
To write an effective scientist, immuno job description, begin by listing detailed duties, responsibilities and expectations. We have included scientist, immuno job description templates that you can modify and use.
Sample responsibilities for this position include:
Perform high-throughput pooled lentiviral CRISPR/Cas9 screens to discover and validate novel immuno-oncology or immunology drug targets and elucidate drug resistance mechanisms
Direct management of up to five direct reports, including research associates and scientific supervisors
Perform immunological assays to interrogate immune cell biology with emphasis on T and NK subsets
Develop, validate, and perform in vitro assays to evaluate drug candidates
Perform in vivo studies using syngeneic tumor models to identify and profile pharmacologic effects of immunotherapeutic strategies and drug candidates
Perform ex vivo pharmaco-dynamic studies tailored to the strategy and target of interest
Participate in discovery-focused large-scale screening efforts
Document, analyze and interpret results from preclinical experiments designed to evaluate therapeutic targets and drug candidates
Conduct studies within timelines to help achieve milestone decisions
Design and execute/conduct in vivo studies (syngeneic and humanized mouse models, GEMMs) aimed at drug discovery in the immuno-oncology space
Scientist, Immuno Qualifications
Qualifications for a job description may include education, certification, and experience.
Licensing or Certifications for Scientist, Immuno
List any licenses or certifications required by the position: HT
Education for Scientist, Immuno
Typically a job would require a certain level of education.
Employers hiring for the scientist, immuno job most commonly would prefer for their future employee to have a relevant degree such as Bachelor's and Master's Degree in Cell Biology, Biology, Oncology, Education, Molecular Biology, Industrial, Biochemistry, Pharmacology, Life Sciences, Biotechnology
Skills for Scientist, Immuno
Desired skills for scientist, immuno include:
Cytokine measurements and other relevant techniques
Procedures used by diverse project groups to support the department where needed
Technologies commonly used to assess immune endpoints
Immunology
Immunology and cancer cell biology preferable
Tumor immunology
Basic immunological mechanisms and tumor immunology
Expertise in tumor immunology
Immunology is crucial
Adaptive immune responses
Desired experience for scientist, immuno includes:
Theoretical and practical knowledge of Next Generation Sequencing sample preparation workflows and applications required
Excellent working knowledge of a breadth of cellular and molecular biology methods
Experience with in vivo tumor models and translational research in the field of immuno-oncology is a plus
Motivated self-starter, with excellent organizational and time management skills with strong communication and presentation skills and attention to detail
Experience with cell culture and basic laboratory techniques
Execute secondary cell-based assays across various technology platforms
Scientist, Immuno Examples
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Scientist, Immuno Job Description
Job Description Example
Our innovative and growing company is looking for a scientist, immuno. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for scientist, immuno
- Implement in-vitro immunologic assays for evaluating activity and mechanism of action of immuno-oncology drug candidates using key immune cell populations
- Develop and perform in-vitro and ex-vivo assays to translate preclinical data into clinical biomarkers for advancing drug candidates through clinical trials
- Critically analyze, interpret, report experimental results
- Participate in Immuno-Oncology team meetings to present data and provide interpretation
- Establish and maintain working relationship with contract laboratories and relevant academic collaborators
- Assume responsibility for writing non-clinical pharmacology study reports, invention disclosures, and contribute to the writing of investigator brochures, IND applications, regulatory annual reports, and other regulatory documents when appropriate
- Works as part of a research team to discover and develop new therapeutic modalities for cancer immunotherapy
- Follows directives of supervisor in an expeditious manner to aggressively complete prescribed timelines and goals
- Independently designs and implements laboratory experiments
- Documents experimental results and plans in laboratory notebooks and in an electronic format accessible to the immediate supervisor
Qualifications for scientist, immuno
- Anticipates needs, assesses and manages business risks and organizational dynamics their implications
- An advanced scientific/medical graduate degree strongly preferred such as PharmD, PhD, or MD and the following
- Significant expertise in vitro screening and validation assays in cancer immunotherapy is required
- Hands on experience with flow cytometry and microplate based assays
- Good understanding and working knowledge with isolation and manipulation of human blood cells, in vitro T cell functional assays
- Board Certification or experience in Oncology/Immunology, Hematology is preferred (>5 years)
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Scientist, Immuno Job Description
Job Description Example
Our innovative and growing company is looking for a scientist, immuno. To join our growing team, please review the list of responsibilities and qualifications.
Responsibilities for scientist, immuno
- Demonstrates innovation in research/planning and expected to be able to make intellectual property submissions
- Demonstrates the ability to manage 1-2 direct reports in a professional manner
- Demonstrates the ability to lead a project team of low-to-moderate complexity and to independently lead project team meetings and scientific discussions
- Implement in-vitro immunologic assays for evaluating activity and mechanism of action of immuno oncology drug candidates using primary cell cultures and patient samples
- Develop in-vitro and ex-vivo assays to translate preclinical data into clinical biomarkers for advancing drug candidates through clinical trials
- Contribute to the writing of investigator brochures, IND applications, clinical protocols, regulatory annual reports, and other regulatory documents when appropriate
- Perform immunological assays to interrogate biology of innate immune cells
- Develop and optimize in vitro assays for evaluation of drug candidates
- Document, analyze and interpret experiments for the evaluation of pre-clinical candidates
- Responsible for design and execution of experiments
Qualifications for scientist, immuno
- Track record of scientific accomplishment and publications in the advancement of new therapeutic concepts
- Strong clinical study experience in Oncology
- Strong clinical, technical or disease area expertise
- Experience with immune profiling in the context of tumorigenesis, and hands-on experience with mouse tumor models is essential
- Requires less than 10% travel, including international
- Candidate should have experience in the isolating, differentiating and manipulating primary human and mouse immune cells experience in growth and maintenance of cell lines, proliferation and apoptosis assays, immunoassay techniques/platforms such as MLR, ELISA, Mesoscale
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Scientist, Immuno Job Description
Job Description Example
Our company is looking to fill the role of scientist, immuno. Thank you in advance for taking a look at the list of responsibilities and qualifications. We look forward to reviewing your resume.
Responsibilities for scientist, immuno
- Participate in Immune Oncology team meetings to present data and provide interpretation
- This position will require good communication skills and collaboratively working with multidisciplinary teams
- Develop and optimize various flow cytometry-based assays for cell surface markers, intracellular cytokines, and other functional assays with primary or iPSC-derived immune cells
- Design and perform laboratory experiments to test hypotheses, interpret results, and troubleshoot experiments
- Lead cross-functional target discovery and technology innovation projects by closely collaborating with multidisciplinary research scientists from diverse backgrounds including human genetics, functional genomics, NGS, lab automation, bioinformatics, statistics, drug discovery, and translational science
- Perform large-scale statistical and bioinformatic data analyses to generate new target hypothesis toward enabling launch of new drug discovery programs
- Present research data to group meetings, project teams, and management, and publish them in external conferences and peer-reviewed journals
- Provide Leadership for the use of innovative Molecular and Cell Biology methods (reporter assay systems, CRISPR, RNAi, lentiviral systems) to identify and validate novel targets in the area of Immuno-Oncology, especially using primary human immune cells (RNASeq experience preferred)
- Manage internal cross site multifunctional project teams in immuno-oncology drug development
- Maintain close effective relationships with different functional groups across the company – particularly in the molecular and cell biology arena
Qualifications for scientist, immuno
- Prior experience in biopharmaceutical industry is strongly preferred
- Candidate should have experience in primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques/platforms
- Candidate should be competent in standard scientific software used for data analysis
- Relevant skills include proficiency in immunological techniques (flow cytometry, intracellular staining, cytotoxicity assays, ELISA, ELISpot, ), cell biology (transient and stable engineering of cell lines, also using viral transduction, immunocytochemistry, microscopy), and molecular biology (molecular cloning, transient and stable gene silencing, methylation specific PCR) techniques
- Theoretical and practical knowledge of Next Generation Sequencing sample preparation workflows and applications preferrred
- Advanced degree in Biochemistry, Molecular Biology, or related required
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Scientist, Immuno Job Description
Job Description Example
Our innovative and growing company is looking for a scientist, immuno. If you are looking for an exciting place to work, please take a look at the list of qualifications below.
Responsibilities for scientist, immuno
- Work closely with external corporate partners to support preclinical, and translational work for immune-Oncology projects
- Provide timely communication of data and present its context and impact
- Attend appropriate external scientific meeting and, where possible, present data
- Draft scientific reports and prepare presentation slides
- Provide unified research-driven innovation and continuous improvement within own Department and across Departments
- May supervise technical staff
- Develop and optimize immunological assays using primary human cells for identification of novel targets and evaluation of drug candidates
- Perform in vivo tumor efficacy studies (murine)
- Immune-phenotying in mouse and human tumors
- Document, analyze and interpret experiments
Qualifications for scientist, immuno
- At least 3-5 years of related experience post education
- Experience in working with primary human and mouse immune cells
- Basic lab techniques including sterile tissue culture and basic cloning / molecular biology
- Individuals with FACS experience are strongly encouraged to apply
- Experience with cell isolation from tissues and Cytof instrumentation would also be an advantage
- BS/MS with at least 3-5 years of demonstrated hands on research experience
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Scientist, Immuno Job Description
Job Description Example
Our company is looking for a scientist, immuno. If you are looking for an exciting place to work, please take a look at the list of qualifications below.
Responsibilities for scientist, immuno
- Use basic molecular biology techniques (ATACseq and/or ChIP-Seq is a plus)
- Thorough understanding of assigned protocol and protocol requirements
- Understands work to be done
- Partner with the Program Lead CRS and CRP to lead the implementation of the global Clinical Development Plans as assigned
- Collaborate with internal research and clinical teams to develop human T cell functional assays, including deep molecular profiling
- Significant experience in multi-color (15+) flow cytometry and cell sorting for downstream analysis
- Independently perform primary cell sorting and ex vivo culture
- Independently develop and drive projects forward
- Participate in management of multiple external scientific collaborations
- Mentor and train other lab members
Qualifications for scientist, immuno
- Good-handle on molecular biology and immunology techniques, including qPCR, multi-color flow cytometry, cell isolation, and in vitro functional assays
- Prior industrial experience with cellular/gene therapies, cell/genome engineering, and in the field of immunology is highly preferred
- It is essential the candidate has an excellent working knowledge of a breadth of immune, cellular, and molecular biological methods (especially immune cell assay techniques including cytokine profiling, isolation, manipulation and phenotypic characterization of primary T cells, multi-color flow cytometry (FACS), viral transduction, molecular cloning, and mammalian cell culture)
- Experience with gene-editing such as CRISPR is also a plus
- Detail oriented and motivated self-starter capable of independently conceiving, conducting and critically analyzing your own innovative research with minimal supervision and excellent lab notebook documentation
- Strong presentation skills, communication and the ability to work in a fast-paced and team-oriented environment will also be vital