Scientist, Immunology Job Description

Scientist, Immunology Job Description

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Scientist, immunology provides content and review relevant sections of regulatory submissions, and help prepare responses to CMC questions from regulatory agencies.

Scientist, Immunology Duties & Responsibilities

To write an effective scientist, immunology job description, begin by listing detailed duties, responsibilities and expectations. We have included scientist, immunology job description templates that you can modify and use.

Sample responsibilities for this position include:

Manage internal and external preclinical immunology activities for drug candidates through discovery and preclinical development
Mentor and develop the immunology scientific staff
Initiates and completes routine molecular, cell and in vitro immunology and pharmacology assays in an independent and efficient manner
Closely work with all other members of the Cellular and Translational Immunology group to support departmental goals
Drive early drug discovery projects in Immunology by designing, conducting, overseeing and analyzing in vitro cellular and translational studies
Contribute to the implementation of the Immunology research strategy
Maintains and develops skills and expertise in immunology clinical and cellular analysis, immunoassays, and company technology through the study of scientific literature, interactions with customers/collaborators, and attendance of conferences
Establish and apply in vitro, in vivo, and ex vivo assays and models to evaluate and advance candidate molecules or novel mechanisms for immunological therapeutic intervention
Participate on cross-functional discovery teams
Independently applies basic scientific principles, performs literature searches, attends scientific meetings, and keeps abreast of literature in own field

Scientist, Immunology Qualifications

Qualifications for a job description may include education, certification, and experience.

Licensing or Certifications for Scientist, Immunology

List any licenses or certifications required by the position: NRP, PALS, BLS, ASCP, HTL, HT

Education for Scientist, Immunology

Typically a job would require a certain level of education.

Employers hiring for the scientist, immunology job most commonly would prefer for their future employee to have a relevant degree such as Master's and Bachelor's Degree in Biology, Cell Biology, Medical, Biochemistry, Molecular Biology, Pharmacology, Biological Sciences, Education, Science, Oncology

Skills for Scientist, Immunology

Desired skills for scientist, immunology include:

Immunology
Laboratory automation software
System software
GLPs and regulatory agencies
Microsoft applications
Computer validation process
Regulatory environment
Relevant instrumentation
Basic and applied research
Biopharmaceutical research and development

Desired experience for scientist, immunology includes:

PhD in relevant scientific discipline (eg
Proposes new experiments/technologies based on science overall understanding of drug discovery/development process
Extensive experience culturing mammalian cell lines and primary human/rodent, immune, epithelial and stromal cells and implementing sophisticated cell-based assays, co-culture and/or organoid model systems
Solid hands-on experience applying multicolor flow cytometry and related analytical techniques to phenotypically characterize cell responses to compounds and antibodies (intracellular cytokines & phosphoprotein staining, cell viability & proliferation)
Demonstrated experience in DNA/RNA isolation (QIAGEN), qRT-PCR/TaqMan, Nanostring and/or RNAseq and DNA transfection and/or retroviral transduction methods employed for in vitro mammalian cell culture models
Adept designing and developing sophisticated cell-based assays with minimal supervision and applying state-of-the-art imaging, biochemical and immunological methods to measure cytokine production, epithelial barrier function (TEER), cell migration, proliferation, apoptosis, cytotoxicity, reporter gene activities, and/or molecular signal transduction pathways in response to small molecule or antibodies

Scientist, Immunology Examples

1

Scientist, Immunology Job Description

Job Description Example
Our growing company is looking for a scientist, immunology. To join our growing team, please review the list of responsibilities and qualifications.
Responsibilities for scientist, immunology
  • Develops an understanding of R&D team goals and works effectively toward achieving them
  • Develops expertise in a specific project-relevant area OR technology
  • Keeps abreast of relevant literature
  • Expertise in immune cell based assays
  • Experience with standard immunological assays and readouts
  • Handle human biosamples and preparation of leukocytes from healthy donors and patients with autoimmune diseases
  • Experience acquiring and analyzing flow cytometry data (multi-parameter FACS, intracellular staining, phosphor-protein analysis)
  • Strong hands-on experience in design and execution of cell-based functional assays using human primary immune cells or subsets for target identification and validation, including pathway based more functional based readouts
  • Able to analyze and interpret data and trouble-shoot with limited supervision
  • Possess a though knowledge of experimental design and underlying scientific principles
Qualifications for scientist, immunology
  • Adept operating liquid handling systems and laboratory plate readers used for in vitro biochemical and cell-based assays (UV/VIS, infrared, fluorescence and luminescence)
  • Good lab hygiene and organization skills and impactful problem solving abilities
  • Experience outsourcing basic molecular biology and reagent production activities
  • Working knowledge of computer software including MS Word, Excel, PowerPoint and additional scientific analysis software (SpotFire, Prizm GraphPad, FloJo XL-Fit or comparable scientific, bioinformatics or statistical data applications)
  • Passionate about science and adept in a fast-paced, nimble, team-based work setting
  • Strong knowledge and experience in various in vitro immune cell assays that are relevant for inflammatory disease areas and experience in biomarker development, FACS analysis, is highly desired
2

Scientist, Immunology Job Description

Job Description Example
Our innovative and growing company is looking for a scientist, immunology. We appreciate you taking the time to review the list of qualifications and to apply for the position. If you don’t fill all of the qualifications, you may still be considered depending on your level of experience.
Responsibilities for scientist, immunology
  • Responsible for assisting in the review, assessment, planning and execution of activities relevant to our GI/immunology drug discovery project portfolio
  • Responsible for the co-leadership of drug discovery efforts, associated pre-clinical de-risking of GI/immunology opportunities, including assisting the clinical development team in providing IND-enabling data
  • Provide documented review and input to the department head/research leadership team on new therapeutic opportunities, competitive intelligence on GI/immunology programs and participates in collaborations with partners regarding disease area activities
  • Coordinate various activities with external commercial vendors RNASeq, autoantibody profiling
  • Proven ability to effectively plan and organize work activities to meet schedules and deadlines
  • Excellent record keeping in electronic laboratory notebooks according to company policy and legal requirements
  • Able to provide timely report of results to project team per request
  • Participate effectively as a member of a “team” within own laboratory and project team
  • Promote the exchange of ideas, information and feedback
  • Provide technical support to colleagues in own area of expertise when necessary
Qualifications for scientist, immunology
  • The individual must have a strong understanding and motivation to link various immunological pathways and their relevance to disease pathogenesis
  • Strong analytical and problem-solving skills with proven track record of high research accountability and productivity both independently with minimal supervision and within a team setting in a matrix environment
  • Appropriate level of understanding of applicable regulations impacting industry R&D
  • Effective communication is essential and includes presentations to effectively convey scientific concepts and data among research scientists, management teams within internal working groups/project teams, external academic and industrial organizations, review committees, and conferences
  • Experience in handling and isolation of primary human immune cells using sterile technique
  • Experience in protein characterization, Western blot
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Scientist, Immunology Job Description

Job Description Example
Our growing company is looking for a scientist, immunology. Thank you in advance for taking a look at the list of responsibilities and qualifications. We look forward to reviewing your resume.
Responsibilities for scientist, immunology
  • Keep abreast with scientific literature and apply the knowledge appropriately to research projects
  • Interpret data, draw conclusions and present results both within and outside of his/her group
  • Must think critically & creatively and be able to work independently
  • Determine appropriate resources for resolution of problems and have strong organizational and planning skills
  • Follow and promote safety instructions and regulations according to Quality Management Standards
  • Designs experimental and data-analysis studies to further develop the TruCulture platform
  • Develops product application literature such as application notes, technical bulletins and white papers
  • Identifies or invents, develops and implements effective solutions for technical issues based on scientific knowledge, evaluation of the scientific literature and laboratory research
  • Manages competing demands with the ability to deal with frequent changes, delays or unexpected events
  • Design and execute in vitro and in vivo studies with an emphasis on modulation of the immune system using novel bio-therapeutic or pharmaceutical approaches
Qualifications for scientist, immunology
  • Experience in diverse types of immunological assays (ELISA, Luminex, immunohistochemistry)
  • Experience in performing gene expression analysis using qPCR
  • Strong sense of work ethic, urgency and creativity
  • Proficiency in scientific computer programs including Microsoft Excel and GraphPad Prism
  • Excellent communication skills and record keeping
  • Excellent organizational skills and safe lab practices
4

Scientist, Immunology Job Description

Job Description Example
Our growing company is looking to fill the role of scientist, immunology. We appreciate you taking the time to review the list of qualifications and to apply for the position. If you don’t fill all of the qualifications, you may still be considered depending on your level of experience.
Responsibilities for scientist, immunology
  • Define immunological pathways triggered during host-pathogen interactions (working closely systems biologists, bioinformaticians and clinical) and their utilization as either intervention points or as biomarkers of efficacy/safety
  • Provide immunological expertise to a variety of project teams in immune mechanisms (innate and acquired) that can be manipulated to provide immunomodulatory therapies
  • Design, plan and perform cell based assays for immunogenicity risk assessment on therapeutic proteins
  • Compile data, write reports necessary for Investigational New Drug (IND) Application under minimal supervision in alignment with partner functions and present conclusions in cross-functional teams
  • Develop new methodologies and improve processes for immunogenicity risk assessment and data analysis
  • Work closely in cross-functional teams in an international setting
  • Provide technical and scientific guidance to team members
  • Develop novel, testable hypotheses through intellectual processes involving literature review, exchange of scientific ideas by participation in internal and external scientific communities, and bioinformatic data mining
  • Design and perform laboratory experiments to test these hypotheses, interpret results and troubleshoot experiments
  • Develop CRISPR functional genomic screening approaches based on in vitro and in vivo immune models to identify and validate key regulators of anti-tumor immunity, and to elucidate molecular and cellular mechanisms behind therapeutic intervention of tumor progression
Qualifications for scientist, immunology
  • Cell-based assay design, development and validation
  • Compound screening and IC50 generation
  • Conduct translational studies using biosamples from patients with autoimmune diseases to support pharmacodynamic and biomarker discovery
  • Characterize immune cells using standard immunological assays that include ELISA, flow cytometry and multiplex assays
  • Execute in vitro functional assays using primary human leukocytes (B, T, DC, Monocytes, etc), handling biosamples from healthy or diseased donors including isolation PBMC or purification of subsets of human leukocytes for the analysis of gene expression, signal transduction and protein readouts to support mechanism of action studies and/or drug candidate assessment
  • Analyze results with limited supervision, and prepare data reports to Lab Head presentations at various forums
5

Scientist, Immunology Job Description

Job Description Example
Our company is growing rapidly and is looking to fill the role of scientist, immunology. To join our growing team, please review the list of responsibilities and qualifications.
Responsibilities for scientist, immunology
  • Lead technology innovations to drive future discovery efforts by taking advantage of available resources in human genetics, genomics, proteomics, automation infrastructure, bioinformatics, and other advanced technologies, and by exercising creativity, innovative thinking, and calculated risk-taking behaviors
  • Learn new skills in functional genomics, lentiviral delivery, flow cytometry, in vivo models, as needed, and productively utilize them in his/her projects
  • Manage cross-functional research projects across therapeutic areas and sites to drive performance and deliver high-quality results in a timely manner
  • Present research data to project teams, larger organizations, and senior management, and publish them in peer-reviewed journals
  • Train and mentor junior colleagues and peer scientists in immuno-oncology, flow cytometry, and/or in vivo biology in matrix project environment
  • Responsible for analysis and interpretation of SPR data generated, in line with industry and regulatory expectations
  • Accountable for delivering new lab developments and method validation on time and within budget
  • Keep project teams informed of project status, technical problems, or other issues which could impact project or service delivery
  • Preparation of protocols and reports in support of method development, validation and execution, in accordance with GxP requirements
  • Act as technical lead and subject matter expert for SPR assays within the organization, with responsibility for training colleagues and advising internal stakeholders and Clients as required
Qualifications for scientist, immunology
  • Contribute to experimental design and provide critical lab support while working in a collaborative team environment
  • Operate common laboratory equipment such as Luminex and QPCR-based expression platforms, as needed
  • Work independently and able to support multiple projects simultaneously
  • Demonstrate ability to design experiments assessing complex biological systems
  • Demonstrate the ability to critically analyze and present data
  • Industry experience is preferred but not essential

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