Scientist, Cell Resume Samples

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M Oberbrunner

Melyssa

Oberbrunner

633 Chaim Parkway

New York

+1 (555) 761 3676

633 Chaim Parkway

New York

Phone

p +1 (555) 761 3676

Experience Experience

Philadelphia, PA

Scientist, Cell Culture

Philadelphia, PA

Stanton LLC

Philadelphia, PA

Scientist, Cell Culture

Efficiently navigate site-wide and global quality systems. May drive SOP/BPR generation, review & approval process and RM qualification. Ensure compliance with cGMP guidelines, quality policies, directives and procedures
Provide technical leadership and mentorship of a small group of scientists and engineers. Ensure worker safety including training, supervision and control of safety guidelines
Plan personnel capacity and equipment resources, experimental setup, analysis and coordination of process development packages for internal and external customers. Participate in process transfers and coordination of interfaces as well as reporting and troubleshooting
Will perform media and solution preparation, maintain cell lines, small scale shake flask production, large scale bioreactor production, cell harvest, and conduct cellular based assays while utilizing aseptic techniques
Responsible for manufacturing product(s) in a lab setting following standard operating procedures. Will utilize basic laboratory techniques, calculations, materials measurement, operation of laboratory equipment and record keeping necessary to manufacture products
May drive SOP/BPR generation, review & approval process and RM qualification. Assist in ensuring compliance with cGMP guidelines, quality policies, directives and procedures
Identify, propose, and execute process and procedural changes to improve process performance, robustness, productivity and efficiency

Phoenix, AZ

Scientist, Cell Line Development

Phoenix, AZ

Tremblay Group

Phoenix, AZ

Scientist, Cell Line Development

Work closely with other members of CLD team, upstream process development and purification teams to support development activities
Perform cell line genetic characterization using methods such as real-time PCR, NGS, and Southern blot to support cell line development and clone selection
Perform and develop immunoassays such as Octet, ELISA, and FAC analysis
Develop CHO cell lines for production of biologic therapeutics using automated platforms for clone screening and management
Manage development projects with outsourcing activities
Provide continued support for generation and evaluation of recombinant CHO cell lines for preclinical development programs
Identify and manage CROs for outsourcing work

present

San Francisco, CA

Senior Scientist, Cell Based Assays

San Francisco, CA

Langosh, Howell and Douglas

present

San Francisco, CA

Senior Scientist, Cell Based Assays

present

Monitor performance of direct reports. Provide regular coaching and counseling for career development
Keep accurate inventory of supplies for laboratory operations, including cell lines banking
Responsible for accurate record keeping with regards to sponsor’s samples, data and reports
Interact with Principal Investigator and/or Scientific Director on all new and on-going projects
Proficiency with standard laboratory calculations, and in the use of standard software including Microsoft® Excel, Word, PowerPoint, etc
Ensure that regulatory guidelines for development and validation of assays and sample analysis are meticulously followed
Write and review final validation reports and QC raw data that go into the reports

Education Education

Bachelor’s Degree in Biology

The Ohio State University

Bachelor’s Degree in Biology

Skills Skills

Has good planning and organising skills with ability for problem solving
Reliable and interested to learn and apply new techniques
Is able to communicate effectively with colleagues and managers within laboratory
Has a keen eye for detail
Is literate, numerate and computer literate
Willing to be involved in working with a team as well as independently
Previous work experience in a scientific area
Has an understanding of working to GMP and GLP compliance

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Scientist, Cell Culture Resume Examples & Samples

Develop scalable processes such as mammalian cell culture and harvest processes for upstream and cell culture development
Lead technology development programs in cell culture in alignment with budget. Propose new technologies for further development
Provide technical leadership and mentorship of a small group of scientists and engineers. Ensure worker safety including training, supervision and control of safety guidelines
Plan personnel capacity and equipment resources, experimental setup, analysis and coordination of process development packages for internal and external customers. Participate in process transfers and coordination of interfaces as well as reporting and troubleshooting
Collaborates within department and cross-functionally to meet set objectives
Efficient, lean & reliable execution and compliant documentation of cGMP manufacturing, with high quality at low cost. Interface effectively with partner organizations both inside and outside of Process Sciences and external partners and customers
Efficiently navigate site-wide and global quality systems. May drive SOP/BPR generation, review & approval process and RM qualification. Ensure compliance with cGMP guidelines, quality policies, directives and procedures

Scientist, Cell Line Development Resume Examples & Samples

Perform key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening, characterization of clonal cell lines using scale-down models, cell banking, and cell line stability studies
Set up new CLD laboratories and develop key methods in CLD to enable in-house development capability of Biologics
Develop and optimize new protein expression platforms including designing, constructing, and evaluating novel expression constructs and expression systems
Host cell development including genetic engineering and media adaptation
Perform and develop immunoassays to support cell line development. These may include ELISA, Octet assay, FAC analysis, and other required assays
Understand IP landscape in novel technologies of molecular biology and CLD and develop corresponding IP strategies and ensure FTO
Identify and manage CROs for outsourcing work
Perform cell line genetic characterization using methods such as real-time PCR, Southern blot analysis, and NGS sequencing
Work closely with other team members within the CLD group, upstream process development, purification process development, analytical and formulation development teams to support discovery and preclinical development activities
Create written technical reports and presents data in project team meetings
Supervise direct reports as the functional team grows
Hands-on experience with generating high producing mammalian cell lines is required
Experience with DNA cloning, vector construction and design, and genetic characterization of production cell banks is required. Experience with NGS-based genomics is a plus
Experience with high throughput immunological assays such as ELISA and Octet assay
The candidate must be well organized and have excellent oral and written communication skills
Must be able to perform well in a collaborative team- oriented and fast-paced environment to meet project timelines

Scientist, Cell Engineering Resume Examples & Samples

Support studies related to the development of cancer immunotherapy products
Support the production and processing of viral vectors
Design experiments independently
Provide bioinformatic support for the group
Successfully execute and document laboratory procedures and experiments with great attention to detail
Work with a cross-functional research team to advance the development of autologous T cell therapy products

Scientist, Cell Line Development Resume Examples & Samples

Candidates highly experienced in cellular and/or molecular biology are encouraged to apply. Prior experience in CHO cell biology is highly desired
Design, execute and analyze platform research studies of biologics to support process development activities which aim to reduce overall timelines while improving cell line productivity and product quality
Provide continued support for generation and evaluation of recombinant CHO cell lines for preclinical development programs
Self-motivated with excellent attention to detail and superb organizational skills, having a proven ability to work in a highly collaborative environment and communicate transversally
Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset
Prepare reports, presentations, and data sets to effectively communicate results, progress and plans
PhD with 0-2 years of relevant experience in Biology, Cellular Biology, Molecular Biology or equivalent industry experience, preferably in Cellular Biology research
Experience in suspension culture of CHO cell lines in a pharmaceutical or biotechnology setting

Scientist, Cell Resume Examples & Samples

Ph.D. in microbiology, immunology or cell biology and experience in developing cellular and immunologically based assays; or equivalent cumulative experience with a lesser degree
Direct hands-on experience in quantitative and qualitative analysis using immunochemistry or cell based assay techniques is required
Strong foundation of knowledge in biological sciences and good aseptic technique is essential
Ability to develop analytical methods to meet international system suitability expectations is desired
Experience training junior scientists is desired
Working knowledge of ICH and USP guidelines and FDA GMP regulatory requirements is desired

Scientist, Cell Culture Resume Examples & Samples

Assist in development of scalable processes such as mammalian cell culture and harvest processes for upstream and cell culture development
Perform comprehensive data analysis of process statistics, identify process deviations, and prepare technical reports
Efficiently navigate site-wide and global quality systems

Lab Scientist Cell Free Functional Assays Resume Examples & Samples

You develop suitable and innovative cell free functional assays for the characterization of therapeutic proteins based on a variety of available technologies. These technologies include SPR (surface plasmon resonance), ITC (isothermal calorimetry),Kinexa, ELISA and will be used to elucidate the “structure-function” relationship of therapeutic proteins. These assays can be used for the characterization or release of proteins for preclinical or toxicological studies
You characterize therapeutic proteins with regard to functionality using cell free assays in the extended characterization of different material
You also have the responsibility for internal documentation, publications, patents and reports necessary for the preparation of regulatory documents
We also ask you to collaborate with international teams to work on strategies and on the harmonization of methods

Senior Scientist, Cell Based Assays Resume Examples & Samples

Function independently in the direction and execution of assigned studies in compliance with GLP regulations
Design, run and analyze experiments in accordance to SOPs and industry guiding documents, and assure appropriateness of immunoassay methods to stage of sponsor drug development process
Interact with Principal Investigator and/or Scientific Director on all new and on-going projects
Supervise the development and validation activities in the laboratory, mentor technical staff and scientists in areas such as protocol interpretation, method development and refinement, study-related problem resolution, etc
Provide technical and scientific expertise in study conduct, design, and interpretation
Review, interpret, integrate, and present validation and analytical data on assigned studies
Participate in the proposal management, quote development process, and sponsor update meetings along with Principal Investigator, Business Development team and/or Scientific Director serving as a key scientific contact for new and existing business partners
Write and review final validation reports and QC raw data that go into the reports
Write Bioanalytical Procedures and SOPs
Ensure that regulatory guidelines for development and validation of assays and sample analysis are meticulously followed
Attend scientific meetings, conferences, and training courses to enhance job and professional skills. Present abstracts/posters at national meetings when appropriate, to maintain a scientific presence and visibility in areas of individual expertise
Keep accurate inventory of supplies for laboratory operations, including cell lines banking
Responsible for accurate record keeping with regards to sponsor’s samples, data and reports
Responsible for general lab safety with regard to employees and clients
MD or PhD with a minimum of 2 years of experience working in a regulated industry environment (GLP/GMP/CLIA); OR
Master’s Degree in Science with minimum of 5 years of industry experience, including at least 3 years of experience working in a regulated environment (GLP/GMP/CLIA); OR
Bachelor’s Degree in Science with minimum of 10 years of industry experience, including at least 5 years of experience working in a regulated environment (GLP/GMP/CLIA)
Minimum of 3 years of cell culture experience
Extensive demonstrated cell-based assay development expertise (Nab assays a plus)
ELISA or similar assay experience preferred
Experience in contract research preferred
Excellent technical writing skills, including SOP writing
Excellent communication skills, ability to handle multiple projects, prioritize work, and meet deadlines
Proficiency with standard laboratory calculations, and in the use of standard software including Microsoft® Excel, Word, PowerPoint, etc

Scientist, Cell Based Protein Biomarkers Resume Examples & Samples

Surveys technology and instrumentation landscape and brings in new technologies to meet the needs of pRED
Builds partnerships with external partners/CROs to increase flexibility and responsiveness when needed
Shows flexibility in developing skills in needed subject areas, technologies or approaches and applying them to projects to support the needs of pRED
Shows flexibility in working with other groups in TTB and throughout pRED to meet needs of pRED portfolio

Scientist Cell Culture / Assay Development Resume Examples & Samples

Perform in vitro cytotoxicity studies to test the potency of ADCs and cytotoxic payloads
Test antibody binding characteristics through ELISA and flow cytometry-based binding and internalization assays
Work independently to develop new and optimize existing analytical assays
Function as a key contributing member of the bioconjugation and analytics team and communicate results across in-house teams
Generate data to support strategic partner relationships, platform development, patents, and publications

Scientist, Cell & Molecular Biology Resume Examples & Samples

Creation of knockout cell lines that could serve as disease models with CRISPR or other technologies
Development of this technology as a possible treatment for monogenetic diseases
Work independently but also contribute to team projects and collaborations, when required
Has primary or shared responsibility for complex projects
May lead a group of one or more research associates. If so, needs to balance scientific and supervisory responsibilities
Participates in scientific meetings
Advanced skills in experimental design, data analysis, and data presentation
Capable of generating quality scientific publications/reports, and oral presentations
Identify opportunities for new project ideas
Ability to supervise and/or train research associates

Scientist Cell Culture, Upstream Development Resume Examples & Samples

Minimum 6 years with a BS, 4 years with an MS, or 0 years with a PhD, of direct experience in the biopharmaceutical/biotech industry
Familiarity with the cGMP principles and how these apply to process development of licensed biological products
Experience of authoring technical documentation and regulatory filing documents
MS/PhD or Post-doctoral training in Chemical/Biochemical Engineering or in a related life-sciences field
7 or more years of experience in the biopharmaceutical/biotechnology industry
Thorough understanding of biology, biochemistry and molecular biology related to recombinant DNA products

Scientist, Cell Line Development Resume Examples & Samples

Performs key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening, characterization of clonal cell lines using scale-down models, cell banking, and cell line stability studies
Develop and optimize new protein expression platform including designing, constructing, and evaluating novel expression vectors and expression system
Perform cell line genetic characterization using methods such as real-time PCR, NGS, and Southern blot to support cell line development and clone selection
Manage development projects with outsourcing activities
Perform and develop immunoassays such as Octet, ELISA, and FAC analysis
Work closely with other members of CLD team, upstream process development and purification teams to support development activities
Serving as SME for data review and development support in cross functional team meetings
Hands-on experience with generating high producing mammalian production cell line is required
Extensive experience with DNA cloning, vector construction and design, and genetic characterization of production cell banks is required. Experience with NGS-based genomic is a plus
Experience with gene targeting and genome editing technologies
Experience with immunological assays such as Octet assay, ELISA, SDS-PAGE, Western blot, and FACS analysis
Proven record on publication in peer reviewed journals and presentation in conference
To be able to perform well in a collaborative team oriented and fast paced environment to meet project timeline

Scientist, Cell Sciences & Technology Resume Examples & Samples

Assist in executing and interpreting experiments in the area of cell culture/bioreactor process development
Perform hands-on bench experiments to characterize in-process and finished samples
Support of bioreactor investigations and coordinate sample testing with colleagues in analytical labs
Data analysis using statistical software packages
Analyze and clearly document experiments in Electronic Lab Notebook (ELN) and Laboratory Information Management System (LIMS)
Evaluate process improvements such as changes in equipment or reagents
Experience with general laboratory practices associated with aseptic/sterile techniques and tissue culture
An understanding of core biology systems and engineering principles
Strong statistical analysis and troubleshooting skills
Ability to work independently, and as part of a larger process development team
Is self-motivated with a high desire to learn new techniques and multi-task with clients
Experience with protein therapeutic process development
Bachelor's degree in Biochemistry, Biology, Life Sciences, Engineering discipline, or other related degree concentration, or equivalent directly-related experience (two years of directly related industry experience is equivalent to one full-time year of college in related major)
Minimum of 1-2 years’ experience; Biotech/pharmaceutical industry experience preferred

Scientist, Cell Line Development Resume Examples & Samples

Develop cell lines for cGMP biologic therapeutics
Serve on Process Sciences teams, defining and documenting production methods. Partner with process teams to assure successful transition of projects between functional groups
Develop CHO cell lines for production of biologic therapeutics using automated platforms for clone screening and management
Skilled in cell and molecular biology techniques including protein expression analysis, vector construction, sequence analysis, genetic analysis, and transfection. Experience with cell imaging and FACS is preferred
Independently plan experiments, analyze data and report findings at early and late stage Project Team meetings
Continuous improvement of methodologies including evaluation and implementation of third party technologies
Authorship of documents in support of regulatory filings
BS in Biological Science with 5-7 years of industry experience or MS and 3-5 years of experience
Demonstrated ability to independently design, execute and interpret critical experiments, and to determine next steps based on outcomes
Demonstrated ability to implement and master new experimental techniques and instrumentation. Ability to multitask across projects while keeping deliverables within timelines
Demonstrated scientific writing and verbal communication skills

Senior Scientist, Cell / Mol Bio Resume Examples & Samples

Routinely demonstrate scientific initiative and creativity in research or development activities
Demonstrates high proficiency across a wide range of relevant technologies
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, and animal care where applicable
PhD; MS; or Bachelor's Degree in Cell/Molecular Biology, Biochemistry, Genetics/Genomics, Pharmacology, Oncology or related field with 0-4+ years (PhD), 8-10+ years (MS) or 10-12+ years (Bachelor's) of experience in cell/molecular biology, apoptosis signaling and/or translational research in Oncology
Previous experience in drug discovery and/or translational research is preferred, but not required
Impactful research experience as demonstrated by track record of publications, patents and/or scientific accomplishments is essential, as is the ability to engage internal and external scientific leaders in collaborative research
Technical proficiency in standard biochemical, cellular and molecular biology techniques with a working knowledge of ‘omics technologies are a must

Scientist, Cell Systems Resume Examples & Samples

Experience of working with synthetic biology tools
Experience working with and development of plant-based transient and stable expression systems
Experience of plant cell culture techniques
Strong skills in molecular biology and various cloning techniques
Ability to address new problems from first principles
Evidence of ability to clearly communicate results and conclusions to non-specialists
Strong background in project planning and experimental design
Ability to drive research in an unprecedented area at BAT
PhD in plant molecular biology or >5 years industry-relevant experience in plant molecular biology
Experience working with Nicotiana spp
Competent in project management
Resourceful, proactive and practical

Scientist, Cell Culture Resume Examples & Samples

Will perform media and solution preparation, maintain cell lines, small scale shake flask production, large scale bioreactor production, cell harvest, and conduct cellular based assays while utilizing aseptic techniques
Requires a minimum of 3 years relevant experience demonstrating laboratory techniques in a manufacturing environment or research laboratory
Demonstrated proficiency in the use of scientific laboratory techniques, equipment and materials required. Experience in the use of basic laboratory techniques, including media and solution preparation, cell expansion, transfection, maintaining cell lines, antibody production, and cellular assays
Familiar with GE Wave bioreactor operation and harvest
Experience with mammalian and insect cell lines
Demonstrated ability to carry out scientific procedures and make recommendations for improvement as required
Good problem solving skills and critical thinking skills are necessary
Displays positive attitude toward job and others
Demonstrated ability to carry out scientific procedures and make recommendations for improvement required
Good problem solving skills necessary

Scientist Cell Culture Resume Examples & Samples

Routine cell culturing to support bioassay testing in accordance with regulatory requirements and agreed schedules
Preparation of reagents and cell culture media to support cell culturing and bioassays
Sample management to support QC testing
Maintain detailed laboratory records in accordance with current Good Manufacturing Practice (cGMP) through the use of controlled proforma or laboratory notebooks
Responsible for the calibration and maintenance of the laboratory equipment, ensuring records are maintained of any calibration, maintenance
Facilitate the ordering of laboratory consumables to ensure efficient running of the laboratory and responsible for the safe storage and/or disposal of test samples, reference materials and reagents following set procedures
Write, review and update SOPs and associated pro-forma used within the laboratory
Reliable and interested to learn and apply new techniques
Education to a Bachelors or higher level in Biochemistry or related subjects
Has an understanding of working to GMP and GLP compliance
Previous work experience in a scientific area
Willing to be involved in working with a team as well as independently
Has a keen eye for detail
Is literate, numerate and computer literate
Has good planning and organising skills with ability for problem solving
Is able to communicate effectively with colleagues and managers within laboratory

Scientist Cell Culture Resume Examples & Samples

O Plan and execute cell culture studies in laboratory with minimal supervision
Hand-on experience with design and execution of cell culture studies in support of process development for mammalian and/or microbial products
Hands-on experience with laboratory or pilot scale automated bioreactors
Deep, broad knowledge of biologics manufacturing process optimization
Experienced in generating experimental protocols, performing data analysis using statistical tools and authoring reports
Direct participation in a biologics product commercialization
Experience with harvest and purification unit operations
Experience with automated high-throughput cell culture systems and integrated analytics