Discovery Scientist Resume Samples

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A Powlowski

Alek

Powlowski

1287 Agustina Fields

New York

+1 (555) 327 8094

1287 Agustina Fields

New York

Phone

p +1 (555) 327 8094

Experience Experience

Los Angeles, CA

Discovery Scientist

Los Angeles, CA

Farrell, Balistreri and Hickle

Los Angeles, CA

Discovery Scientist

Partner with breeders to develop novel technology-based breeding concepts to increase speed to market, breeding efficiency and improve hybrid performance
Design and perform cellular and molecular experiments and assays
Supervise and guide junior research associates and work study students
Manage multiple experiments and projects simultaneously
Recruit, train and develop research personnel
Develop plant populations, design experiments and collect phenotypes for traits of interest
Conduct linkage, QTL, and association analysis to identify and tag genes of interest with molecular markers

San Francisco, CA

Scientist, Genomic Technologies, Discovery

San Francisco, CA

Walsh-Swaniawski

San Francisco, CA

Scientist, Genomic Technologies, Discovery

Perform genomic profiling analysis with the highest standards of scientific rigor
Process and perform QC analysis of samples from tissues and cells
Perform initial data QC and first pass analysis of results
Deliver high quality data and results under agreed upon timelines
Effectively communicate with stakeholders, especially around trouble-shooting and responding to changes in priorities and adjusting timelines
Partner with bioinformatics specialists and disease area scientists to interpret results and design follow up experiments
Operate and maintain genomic technology platforms within centralized technology group

present

Houston, TX

Senior Discovery Bioanalytical Scientist

Houston, TX

Harber, Harris and Smith

present

Houston, TX

Senior Discovery Bioanalytical Scientist

present

Activity contribute to research and early development teams when called upon
Proven track record of developing innovative lab based bioanalytical solutions to complex technical challenges
Drive the scientific discussion and rational for all bioanalytical endpoints including biomarkers
Contribute to the preparation, design and review of study protocols, reports and associated documents
Keep abreast of latest technologies and publications in the field of bioanalysis
In-depth knowledge of laboratory equipment and instrumentation, with particular focus on MS instrumentation (MS/MS and/or HRMS data collection and basic interpretation; instrument trouble shooting) developed over ca. 10 years in Pharma or CRO environment
Resolving technical challenges in the laboratory including but not limited to resolving selectivity issues , improving sensitivity, ensuring method precision and accuracy is fit for purpose

Education Education

Bachelor’s Degree in Cell

Iowa State University

Bachelor’s Degree in Cell

Skills Skills

Demonstrate clear and professional verbal and written communication (excellent presentation skills)
Excellent oral and written communication skills. Able to effectively present scientific data and concepts to international standards
Detail-oriented, with excellent record-keeping skills
Excellent interpersonal skills with the ability to interact effectively with people, internally and externally
Strong organizational skills including the ability to manage several projects simultaneously
Interpret, troubleshoot and report on complex data. Basic statistical knowledge is mandatory
Intellectually curious and well-informed on the latest scientific advances in the field of solid tumor and immune oncology
Strong capabilities to collaborate with scientists in multiple disciplines
Demonstrate the ability to design/ execute decision making experiments and interpret, troubleshoot and report complex data
Present data in professional 'publication ready' format

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15 Discovery Scientist resume templates

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Discovery Research Scientist Resume Examples & Samples

Run routine cellular assays to determine activity of modulators and deliver high-quality data to Project Teams in a timely fashion
Identify novel targets for inclusion in I&I drug discovery portfolio
Meet regularly with supervisor to provide verbal and/or written progress reports. Present data as required at Project and Departmental meetings. Must be able to keep current with electronic lab notebook

Discovery Scientist Resume Examples & Samples

Demonstrate the ability to design/ execute decision making experiments and interpret, troubleshoot and report complex data
Experimental work utilizing diverse expertise in cell/molecular biology/ biochemistry: eg transfections, transductions, western blotting, immunoprecipitation, siRNA/shRNA, FACS, ELISA, basics in enzymology (eg KD, KM etc)
Ability to perform tissue culture is a must
Successful implementation of innovative small and large molecule drug discovery strategies: eg screening funnels, PK/PD/Efficacy correlations etc
Supervise and engage junior research associate(s)
Demonstrate the ability to contribute on various projects even outside of his/her responsibility and comfort zone by collaborating with stakeholders from all relevant functions
Related Experience
Personal skills and Competencies
Intellectually curious and well-informed on the latest scientific advances in the field of solid tumor and immune oncology
Demonstrates creativity and novel approaches to solving scientific problems

Drug Discovery Scientist Resume Examples & Samples

Degree in chemistry, biochemistry, or related field
Experience in pharmacology
Experience working in a lab setting
Experience conducting and evaluating experiments and assays
Independent research experience

Drug Discovery Data Scientist Resume Examples & Samples

The translation of questions of disease experts in the therapeutic areas and wet lab colleagues, to a quantitative analysis formulation
The design and execution of targeted analysis approaches to link processed molecular and cellular data at scale to pathophysiological processes or clinical outcome, to produce actionable conclusions and to inform decision making
The development and internalization of rigorous state-of-the-art approaches for integrative data analysis, and build-out and leveraging of collaborations with leading academic and industrial scientific teams in life, computational and data sciences
Work with informatics and statistics colleagues to offer the resulting analysis and visualization solutions to the project teams
Contributing to the scientific weight of the department by authoring peer-reviewed papers and presenting at relevant conferences
PhD in Computational Biology or any related quantitative field with direct exposure to multidisciplinary biology or clinical context with ideally a few years of post-doctoral experience in an academic or industrial setting
Demonstrated experience with linking high-dimensional molecular data, to phenotypic or clinical outcomes in constellations that led to hypothesis driven experimental or clinical follow-up
Advanced programming and scripting skills that enable the development of functional prototypes
Excellent communication, reporting and team interaction skills, self-motivation, proactivity and the ability to work independently

Discovery Scientist Oncology Resume Examples & Samples

Ability to perform tissue culture is a must. Cell/molecular biology skills: transfections, transductions, western blotting, immunoprecipitation, siRNA/shRNA, qRT-PCR, FACS and ELISA. Some experience working with in vivo models is a plus (direct handling not required for this position)
Experience in drug discovery is important (large or small molecules, PK/PD, understanding of drug properties, assay / model development, drug testing, etc)
Supervise and guide junior Research Associates (by example)
Demonstrate the ability to contribute on various projects outside of his/her own, and collaborate with stakeholders from all relevant functions
Ph.D.degree or equivalent, with several years of productive post-doctoral experience in a high-quality academic, biotech or pharmaceutical environment is required
Knowledge of oncology, hematology, or immunology with a track record of high-quality publications is essential
Knowledge of pharmacology is important
Intellectually curious and well-informed on the latest scientific advances in the field
Able to demonstrate creativity and novel approaches to solving scientific problems
Some management experience is very desirable

Scientist, Oncology Discovery Resume Examples & Samples

Ability to supervise and guide junior Research Associates
Ph.D.degree with some post-doctoral experience is required
Drug discovery experience in a biotech or pharmaceutical environment is preferred
Knowledge of pharmacology is preferred
Cell/molecular biology skills are required (ie: transfections, transductions, western blotting, immunoprecipitation, siRNA/shRNA, qRT-PCR, immunofluorescence, FACS and ELISA)
Experience working with immune assays are required (ie: ADCC, cytokine release, T cell biology, immune cell purification and characterization)R&D

Scientist Iv-therapeutic Discovery Resume Examples & Samples

Contractor will be a Principal Investigator (PI) focused on applying state of the art techniques and emerging research technology such as synthetic biology to elucidate novel mechanisms of bacterial pathogenesis and identify novel targets and therapeutic small molecules
The Contractor will develop novel whole-cell reporter and biosensor assays based on Fluorescence; luminescence; and Fluorescence Resonance Energy Transfer (FRET) platforms. Integral to this Task is the development of novel assays designed to measure the efficacy of therapeutics in both in vitro and in targeted microbial systems and animal models of infection
Contractor will employ expertise in bacterial physiology to utilize bacterial quorum sensing systems as a target of MCM development. This requires a strong working knowledge of quorum sensing modulations by natural and synthetic compounds and other molecular mechanisms
Contractor will provide expertise in performing standard molecular biological techniques and molecular microbiological experiments to genetically manipulate bacteria to understand contribution of genetic determinants to virulence and antimicrobial resistance to provide laboratory support to ongoing research efforts within the Division. In addition the Contractor will help train junior members of the research team in research techniques; assist team in drafting animal protocols; designing experiments; troubleshooting technical issues; and writing manuscripts
As a Principal Investigator; seek funding from DTRA and other funding agencies on behalf of the Government and USAMRIID to further the research portfolio of MTS and USAMRIID. Establish and coordinates extramural collaborations and contracts; to augment the research program he or she directs. Amounts of funding per year will vary depending on current mission requirements and USAMRIID's available funding
The Contractor will record; analyze; interpret and wherever possible publish experimental data. As a Principal Investigator; they should prepare technical reports and manuscripts for publication each year. They should present work at Scientific Meetings each year; which may require CONUS and OCONUS travel
Experience in the development of medical products for licensure by the FDA is desired

Drug Discovery Scientist Resume Examples & Samples

Conduct cell-based and plate-based assays to enable drug discovery efforts
Use established protocols and existing assays to measure growth inhibition, apoptosis, regulation of transcription, and inhibition of signaling pathways; assays include fluorescence- and luminescence-based formats, such as ELISA, In-cell Western, and FRET
Screen compounds in single concentration and dose-response schemes, analyze and report data
Contribute to the design and development of novel assays to measure the functional consequences of inhibition of a number of diverse targets, including assays to measure disruption of protein-protein interactions, anchorage-independent growth, migration, invasion, and signaling
Conduct research projects to understand the mechanism of action of novel targeted therapies identified in our group. This may include screening cancer cell lines and tumors to understand the genetic predictors of response to these targeted agents
Suggest, design, and implement research projects to identify and validate new targets for cancer drug discovery. Experiments may include target silencing by RNAi, target overexpression, and compound treatment of cancer cell lines
Remain current on literature, ideas, and relevant laboratory techniques in oncology and drug discovery
Contribute to the effective operation of the lab by sharing the responsibilities of preparing buffers and reagents, ordering supplies, and maintaining equipment
Ph.D. or Master’s degree in cell or cancer biology preferred
5 years’ experience in oncology/cancer biology
Experience in compound screening or drug discovery in a pharmaceutical or biotech company preferred
Experience in standard cell biology techniques, including mammalian cell culture, transfection protocols, Western blotting techniques, fluorescence microscopy, and PCR
Ability to design and troubleshoot assays and experiments independently
Clear written and oral communication skills
Excellent data analysis capabilities and proficiency with curve-fitting and graphing programs

Scientist, Early Discovery Resume Examples & Samples

This individual will be responsible for the identification and evaluation of new targets and novel therapeutic mechanisms to advance our early discovery pipeline. This includes setting project strategy, being accountable for the advancement of individual programs and working directly in the lab to prosecute on targets
Work cross functionally with several groups (Chemistry, Biochemistry, Protein Sciences, Pharmacology) to initiate and advance new targets and areas of biology as well as our Business development group in the assessment of external opportunities
Share responsibility for maintaining an innovative early discovery research infrastructure
Present strategy and data in a variety of settings
Potential to manage junior scientists contributing to projects
The candidate may also play a large role in strengthening and expanding our research relationships with the external community to establish strategic collaborations as well as serve as a company liason with partners

Scientist CNS Discovery Resume Examples & Samples

Conduct independent laboratory research in the area of preclinical CNS drug discovery. Responsible for all aspects of initiating and executing in vitro and ex vivo assays, including: identification of appropriate assays, experimental design, assay development and validation, statistical analyses, and reports
Work with team members on a project basis to facilitate timely execution of high quality studies
Rigor in experimental design and data interpretation is essential. Identify effective next steps and go / no go experiments with a focus on program needs
Interact with program teams to identify, plan, and carry out program goals. Report experimental results to supervisor, to teams, and to site
Ph.D. in neuroscience, pharmacology or a related discipline with at least one postdoctoral training experience
Solid knowledge of neurobiology and of its application to create assays relevant to the investigation of targets to CNS diseases
Experience with IPSCs/stem cell research
Ability to work well in a small group and capable of working closely and collaborating with other scientists
Experience in neuroinflammation /neurodegeneration research desirable

Discovery Scientist Resume Examples & Samples

Conduct linkage, QTL, and association analysis to identify and tag genes of interest with molecular markers
Develop plant populations, design experiments and collect phenotypes for traits of interest
Analyze phenotypic, genetic and genomic data sets using advanced IT and statistical tools, as well interpret and communicate results
Partner with breeders to develop novel technology-based breeding concepts to increase speed to market, breeding efficiency and improve hybrid performance
Support Monsanto's freedom to operate by filing invention disclosures and supporting patent applications
Recruit, train and develop research personnel
Ph.D. in genetics, plant breeding, genomics or related field
Knowledge and experience in experimental design, statistical analysis and relevant software applications
Knowledge in methods of plant breeding and quantitative genetics
Ability to manage complex projects and lead interdisciplinary teams to accomplish project goals within expected timelines and budget
Outstanding analytical and communication skills
Strong initiative and results orientation
Excellent command of English (written and oral)
Postdoctoral training and/or prior research experience in the industry
Experience in the use of molecular markers for genetic mapping of traits
Experience in disease resistance traits and/or plant pathology
Experience in methods of genomics and bioinformatics, and/or analysis of genome sequence data to support testing of targeted genetic hypotheses
People leadership experience

Scientist, Oncology Discovery Resume Examples & Samples

Demonstrate the ability to design, perform, interpret, troubleshoot, and report complex data
Demonstrate the ability to contribute on various projects outside of his/her own, and collaborate with stakeholders from all relevant functions; some experience working with in vivo models is a plus (direct handling not required for this position)
Excellent presentation skills including clear and professional verbal and written communication
B.A./B.S. with at least 8 years pharmaceutical research experience OR a M.S. with at least 4 years pharmaceutical research experience OR a PhD with relevant research experience is required
Experience in the cancer field is preferred
Experience in drug discovery (i.e.: large or small molecules, PK/PD, understanding of drug properties, assay/model development, lead screening and profiling) is preferred
Previous experience setting up cell based assays (proliferation, ELISAs, transfections, siRNA/shRNA knockdown) and with stable clonal cell line generation is preferred
Experience with techniques such as western blotting, immunoprecipitation, qRT-PCR, immunofluorescence is preferred
Experience isolating and characterizing immune cell populations from whole blood or tissues and setting up immuno-assays (i.e.: ADCC, cytokine release, T-cell biology or other functional assays) is preferred
Previous leadership experience (coaching, mentoring, leading projects) is requiredR&D

Senior Discovery Bioanalytical Scientist Resume Examples & Samples

Resolving technical challenges in the laboratory including but not limited to resolving selectivity issues , improving sensitivity, ensuring method precision and accuracy is fit for purpose
Drive the scientific discussion and rational for all bioanalytical endpoints including biomarkers
Evaluate a broad spectrum of available technologies to ensure quantitative assay are fit for purpose
Activity contribute to research and early development teams when called upon
Capable of developing bioanalytical method that can meet the requirements of regulatory bioanalysis needs
Function as a laboratory leader capable of mentoring colleagues and provide guidance were required to other bioanalytical scientists&#8217
Well organized, capable of communicating clear instruction to partners and stakeholders
Contribute to the preparation, design and review of study protocols, reports and associated documents
Keep abreast of latest technologies and publications in the field of bioanalysis
Experience in the pharma or CRO industry supporting discovery and preclinical development bioanalytical activities primarily for NCE programs
In-depth knowledge of laboratory equipment and instrumentation, with particular focus on MS instrumentation (MS/MS and/or HRMS data collection and basic interpretation; instrument trouble shooting) developed over ca. 10 years in Pharma or CRO environment
Proven track record of developing innovative lab based bioanalytical solutions to complex technical challenges
Extensive knowledge of a range of bioanalytical techniques to support chromatographic method development, extraction from a range of biological matrices (including but not limited to plasma, urine and a range of soft and hard tissues) and mass spectrometry
Extensive knowledge early drug development including experience supporting DMPK, PK/PD and pharmacology studies
Experience working with a wide range of internal stakeholders to including a range of DMPK, investigative ADME, Chemistry, Pharmacology and Non-Clinical Safety colleagues
Previous experience as a bioanalytical project representative would be ideal
Demonstrated ability to influence teams to ensure bioanalytical data generated is of the highest quality
Experience with High Resolution Mass Spectrometric (HRMS) technologies would be desirable
Proven track record of engagement in the external bioanalytical community via publications and presentation at international conferences on a regular basis

Scientist, Discovery Antibiotics Resume Examples & Samples

Play an active role in a diverse team of scientists in a fast pace and science-driven environment with the goal to discover and develop novel medicines for the treatment of bacterial infections
Contribute to development and testing of novel candidate antibiotics, determine efficacy and elucidate their mode of action
Support scientific projects by developing and implementing novel assays and providing reliable experimental results
Perform routing antimicrobial assays such as MIC, checkerboard assays, time-kill kinetics, frequency-of-resistance, resistance rate, and resistance stability

Drug Discovery Scientist Resume Examples & Samples

Independently synthesize compounds to investigate and interpret structure-activity relationships
Plasma protein binding for humans and various animal species
Brain protein binding with rodent homogenates
Perform synthetic organic and medicinal chemistry, parallel synthetic techniques, large-scale synthesis and DMPK interpretation/incorporation in drug design
Supervise junior scientist in chemical synthesis, data analysis, and instrumentation use
Extensive operation, instruction, and maintenance of analytical instrumentation such as liquid chromatography mass spectroscopy, nuclear magnetic resonance, and automated flash column chromatography

Scientist, Oncology Research Discovery Resume Examples & Samples

Demonstrate the ability to contribute on various projects outside of his/her own, and collaborate with stakeholders from all relevant functions; some experience working with in vivo models is a plus (direct animal handling is not required for this position)
Keep up-to-date in the literature related to his/her field. Act as an expert resource in his/her scientific field and in related disciplines
Excellent presentation skills (including clear and professional verbal and written communication) are essential
Ability to supervise and mentor Research Associates
Ph.D. degree in biochemistry, molecular biology, pharmacology, cancer biology or related field with relevant experience OR a B.S. or M.S. degree with at least 6 years of industry experience in cancer therapeutics is required
Relevant cancer research experience is required with a strong track record of publications
Experience in prostate cancer biology and/or tumor immunology is preferred
A strong background in cellular and molecular biology laboratory techniques is required
Knowledge of mechanisms of transcriptional regulation in prostate cancer is preferred
Experience isolating and characterizing immune cell populations from whole blood or tissues and setting up immuno-assays is preferred

Scientist, Antibody Discovery Resume Examples & Samples

PhD with 0-3 years of experience in the biotech/pharmaceutical industry. Ideal candidates will have completed successful post-doctoral research and have a strong publication record
Significant understanding of immuno-oncology and/or the innate immune response
Expertise in one or more of the following: biochemistry and protein engineering, identification and validation of cancer targets, and models of immune modulation
Experience with large data analysis is a plus
Experience with biologics or antibody therapeutics is a plus
Excellent interpersonal skills to work effectively in team environments is required

Principal Scientist, Antibody Discovery Resume Examples & Samples

Provide insights/expertise to the design and implementation of antibody/protein based discovery strategies for the identification and validation of therapeutics for inflammation and immuno-oncology
Generate reason-to-believe data to initiate new project opportunities - conduct, and supervise laboratory personnel in designing and execution of screening assays
Design and conduct biochemical and biological assays to elucidate MOA, evaluate /refine bispecific and other antibody formats to inform in-vivo models to support selection of candidates for lead optimization and development
Ensure optimal target engagement and therapeutic activity of candidates
Identify and manage contract research laboratory studies for antibody and/or alternate scaffold discovery
Ph.D. in Molecular Biology, Cell Biology, Genetics, Protein Chemistry, Immunology or related field and at least 8 years work experience in drug discovery working with biologics and development
5+ years experience working in the biotech/pharmaceutical industry in drug discovery required
Demonstrated prior experience managing CRO's required
Subject matter expertise in antibody discovery (displays systems, humanized rodents, NGS etc.) is essential to this role
Ability to work independently as well as in a multi-discipline team environment
Ability to interface effectively with business partners - effective communication and interpersonal skills
Ability to embrace a culture of continuous learning and improvement, increasing technical skill base and disease biology expertise
Track record in scientific publications

Scientist, Molecular Discovery Resume Examples & Samples

Expertise in mammalian tissue culture
Experience producing antibodies from hybridomas
Experience with quantitation methods using Octet
Experience with data base and lab information management systems

Scientist, Genomic Technologies, Discovery Resume Examples & Samples

Perform genomic profiling analysis with the highest standards of scientific rigor
Collaborate to design the best possible experiments
Deliver high quality data and results under agreed upon timelines
Process and perform QC analysis of samples from tissues and cells
Perform initial data QC and first pass analysis of results
Partner with bioinformatics specialists and disease area scientists to interpret results and design follow up experiments
Operate and maintain genomic technology platforms within centralized technology group
Keep current on rapidly evolving genomic technology platforms, especially DNA microarrays, RNA-Seq, DNA-Seq, and digital PCR. Contribute to technology development efforts as needs arise
Work with external CROs and technology providers as needed to complement internal capabilities and address spikes in demand
MS in molecular biology, genomic sciences or a related field with 5+ years of experience, or BS with 7+ years of experience
Strong record of hands-on experience and technical knowledge of genomic profiling technologies, including but not limited to: RNA-Seq, DNA-Seq, Affymetrix GeneChips, and NextGen PCR technologies
Experience being part of a centralized technology group is desirable
Expert and detailed knowledge of genomic sample processing, sample QC, genomic profiling data QC and analytical methods
Familiarity with LIMS, sample tracking and workflow optimization
High attention to detail, strong written and verbal communication skills, ability to work independently and as part of teams
Ability to work in fast-paced, dynamic environment and to independently carry forward multiple projects in parallel

Principle Scientist, Discovery Immunology Resume Examples & Samples

Utilize multiple preclinical models to evaluate novel therapies in autoimmune models especially in rheumatoid arthritis
Perform studies using ex vivo models related to rheumatoid arthritis and other autoimmune process
Interface with external CROs to conduct studies in preclinical models of autoimmunity
Lead biology efforts supporting target identification and optimization for drug discovery programs while working with internal and external partners and collaborators
Contribute to strategic planning of drug discovery programs
Effectively document, interpret, and communicate results and data
A PhD in Immunology or related scientific discipline with at least 5 years of pharmaceutical industry and/or equivalent academic experience is required
Post-doctoral training is preferred
Experience in either RA and/or leading Immunology discovery projects is required
Solid background in Immunology is required
Deep understanding of lymphocyte functions, tolerance and autoimmune mechanisms is preferred
Experience leading and advancing drug discovery programs, both small molecule and large molecule drugs, in immune-mediated diseases is preferred
Previous leadership experience (coaching, mentoring, leading projects) is required
Up to 10% travel is requiredR&D

Discovery Scientist Resume Examples & Samples

Ability to perform proper tissue culture is a must. Cellular and molecular biology techniques include: microscopy, immunocytochemistry, flow cytometry, transfections, transductions, RNAi and CRISPR/Cas9, RTQ-PCR, western blotting, immunoprecipitation etc
Keep up-to-date on literature related to his/her field. Act as an expert resource in her/his scientific field and related disciplines. Propose novel and actionable assay ideas, aligned with internal and external scientific strategies and demands
Communicate in a clear and professional manner, both orally and written
Strong capabilities to collaborate with scientists in multiple disciplines
Strong record of publications

Senior Scientist, Early Target Discovery Resume Examples & Samples

Leads a group of scientists in development of new technologies to expand the capabilities of the bacTRAP group
Assesses and accesses external technology to enable the most effective and technically current operation of the group
Leads the design of new BAC, plasmid and viral constructs for the genetic profiling and manipulation of physiologically important cell types in vivo
Applies expertise in mouse genetics and vector design to plan and undertake cell specific transgenic approaches and in vivo gene delivery experiments
Rapidly and efficiently transfers newly developed technologies to the core bacTRAP group for routine use
Works closely with the core bacTRAP group to optimize the use of newly developed technologies for specific projects
Establishes the routine use of stereotactic injections using a variety of chemical compounds, viral vectors, and anatomical tracers as needed for genetic and pathway assessment, molecular profiling, and physiological studies in vivo
Works and communicates effectively with colleagues of differing backgrounds and experience levels
Represents the Department at project team meetings and scientific meetings
Keeps up to date with appropriate literature and scientific developments and use knowledge to propose new programs or support current programs
Ph.D. in relevant field of biology with 4+ relevant years of experience OR
MS/MA with 14+ relevant years OR
BS/BA with 16+ relevant years
Experience in manipulating the expression of biological targets in vivo and in vivo pharmacology
Breadth of knowledge in existing and developing molecular technologies, including bacTRAP, CRISPR/Cas9, Single cell seq, RNAseq, IPSCs, GCaMP, and human genetics
Strong background in using and/or developing new technologies for in vitro and in vivo transcriptional regulation and assessment of gene function
Highly experienced in in vivo gene delivery systems
Well versed in technologies used for activating or inhibiting specific cell types using optogenetics and/or RASSLs/DREADDs
Management of multiple tasks of varied complexity simultaneously
Skilled in statistical analysis, graphing programs and PowerPoint presentations
Effective presentation skills – create and deliver presentations with appropriate messaging and focused recommendations

Scientist, Discovery Preformulation Resume Examples & Samples

Collaborate with discovery partners to evaluate molecular properties relevant to drug delivery and influence team strategies
Design and develop fit-for-purpose preclinical formulations (conventional and enabling) for pre-clinical toxicological and PK/PD studies to enable robust candidate selection and progression
Assess and clearly communicate drug delivery and performance risks. Perform fit-for-purpose analytical method development for small molecules and peptides, forced degradation analysis and preformulation studies, solubility measurement, solid-state characterization using techniques such as, particle size measurement, XRPD, DSC, TGA, vapor-sorption analysis etc
Maintain an awareness of and contribute to scientific literature; actively apply delivery technologies to projects as appropriate. Conduct research and present significant findings via internal and external presentations or publications
Ph.D. in Chemistry, Pharmaceutical Sciences or related disciplines with or without any industrial experience OR MS in Chemistry, Pharmaceutical Sciences, or related disciplines with equivalent industrial experience (3+ years) will also be considered
Outstanding written and oral communication skills are required
Strong theoretical background and hands-on experience in one or more of the following areas is preferred: physicochemical characterization of small molecules/peptides, conducting solubility measurements, manufacturing enabling formulations such as nanosuspensions/solid dispersions, and conducting preformulation studies.R&D

Scientist Antibody Discovery Resume Examples & Samples

2 years’ experience in one or more antibody discovery technologies (e.g. hybridoma, phage display, B cell recovery (SLAM), nanoscale screening, gel microdrop, NGS, etc.)
Knowledge of FACS based binding assays and analysis
3+ years' relevant post-doctoral research or equivalent industry experience in therapeutic antibody discovery field
Proficiency in screening characterization platforms; Biacore, ForteBio, etc
Large molecule discovery and development experience
Demonstrated Group management/leadership experience
Experience in a working environment requiring strong inter-personal and communication skills across a broad range of audiences including senior scientists and leaders throughout an organization
A consistent record of scientific achievement including innovation, collaboration and publication
Experience in a role requiring strong problem solving and scientific skills
IP creation

Scientist, Oncology Discovery Resume Examples & Samples

Characterize new targets and pathways in the immune system that can be modulated for cancer immunotherapy. This work will be conducted as part of a multidisciplinary research team in a fast-paced and well supported discovery environment under the mentorship of a supervisor
Utilize strong working knowledge in immunology and/or cancer research and extensive hands-on experience to identify, validate and characterize novel immunological pathways and/or therapeutics
Interpret results and draw conclusions from multistage experiments and suggest, design and pursue relevant experiments that further project goals
Understand relevant scientific literature and apply a theoretical framework to solving problems in a timely manner
Independently schedule and prioritize workload to manage several tasks simultaneously and identify / utilize resources outside of own group

Co-op Scientist, Early Discovery Neuroscience Resume Examples & Samples

Design, execute, interpret and report in vivo experiments
Assist in developing, executing, and troubleshooting in vivo assays using mouse models of Alzheimer’s disease
Support characterization and validation of antibody and small molecule activities in in vivo models
Collaborate with members from other functional areas, including medicinal chemistry, imaging, protein sciences, in vivo and in vitro pharmacology and genetics
Neuroscience class work
Some experience with in vivo (rodent) techniques
Some experience with basic lab procedures: pipetting, solution preparation
Preferred experience with stereotaxic surgery, animal handling
Experience with rodent behavior and dosing procedures a plus
Preferred experience with western blot protocols or ELISA assays
Demonstrated ability to perform accurate data analysis
Excellent oral and written communication skills, including preparation of lab reports and presentations. Strong attention to detail

Antibody Discovery Scientist Resume Examples & Samples

Performance of the hybridoma process including: hybridoma generation via cell fusion, selection, and automated colony picking, primary characterisation of hybridoma-derived antibodies using both biochemical and cell based screens, sequence analysis of hybridoma clones, and hybridoma propagation and antibody purification, to support therapeutic projects in their identification of lead antibodies
Independently analyse and interpret data, and recommend revision of experimental strategies accordingly and present to Hybridoma function leader
Organise own and team’s lab work for a given project to enable smooth progress and project completion within agreed timelines
Record experiments in lab books and databases
Complying with current health and safety codes of practice and quality initiatives
Ph.D. or equivalent experience in Molecular Biology/Cell Biology/ Biochemistry
Demonstrated laboratory skills in molecular biology and basic cell culture
Experience of performing routine biochemical assays (e.g. ELISA, HRTF)
Basic cell culture practices and aseptic technique
Routine molecular biology techniques (e.g. PCR, cloning, sequence analysis)
Experience with hybridoma generation
Experience working with primary cells
Experience of performing cell based assays
Practical experience of protein/antibody engineering
Experience of assay development and troubleshooting
Understanding of methods of protein/antibody engineering

Scientist, Discovery Immunology Resume Examples & Samples

Driving on-going projects with relevant assays to understand MOA and facilitate decision points
Proposal of novel ideas and targets as well as presentations to peers and senior leaders, establishing appropriate assays, execute and analyze data, and presentation of findings to peer scientists
Targeting major cell surface and intracellular targets involved in the modulation of immune cell responses and tolerance
Collaborate and interface with cross functional groups and functions to generate required support for the projects using excellent oral and written skills
PhD in immunology, with a focus on immune mechanistic pathways involved in autoimmunity, with at least 1 year of relevant post-doctoral experience OR a MS in immunology, with a focus on immune mechanistic pathways involved in autoimmunity, with at least 5 years of relevant experience is required
At least 2 years of previous industry experience and the demonstrated ability to work independently and as part of an interactive team in a fast paced, matrix environment is preferred
Strong expertise in establishing cell based assays to measure functions of immune cell subsets in vitro is required
Capability to develop and study complex cell assays systems to understand disease mechanisms in required
Prior experience in models of RA and other autoimmune disease and developing therapeutics is preferred
Experience leading projects, designing studies to investigate MOA and drive to go/no-go decisions is preferred
Strong background in immunology, lymphocyte biology, autoimmunity and tolerance with specific application of these principles to inflammatory disorders is required
An understanding or prior experience with biomaterials and formulations is preferred6100170403

Scientist, Discovery Immunology Resume Examples & Samples

A PhD in Immunology/pharmacology with at least 1 year of pharmaceutical industry or academic experience OR a MS in Immunology/pharmacology with at least 5 years of relevant experience is required
Experience with development of complex cellular systems to mimic aspects of human disease and uncovering novel biology relevant to human immune-mediated diseases is preferred
Solid background in Immunology/Pharmacology is required
Strong understanding of Lupus disease pathophysiology and immunological pathways, particularly in B cell biology is preferred
Experience in industry drug discovery (small or large molecule) is preferred
Experience in in vitro and in vivo assays to assess B cell activation and function is preferred7687170411

Scientist Target Discovery Group Resume Examples & Samples

Participate in multi-laboratory collaborations to characterize novel drug targets and therapeutic approaches for cancer drug development
Responsible for validating novel oncology targets and biomarkers
Delineate the clinical path for novel small molecule inhibitors
Responsible for pre-specified deliverables to external industry partners within specified timelines
Mentor and manage a group of scientists to deliver innovative results
A Ph.D. in molecular biology, cancer biology, or biological sciences
2-3 years post-doctoral experience
Experience in CRISPR genome editing is desired
Experience and expertise in flow cytometry is preferred
Demonstrated scientific excellence & scientific rigor
Independent, self-motivated and innovative
Strong management and organizational skills
Ability to work productively & constructively in a team environment
Ability to excel in a goal-oriented, multifaceted and fast-moving team environment
Industry experience is a plus

Mechanistic Investigative Discovery Scientist Resume Examples & Samples

Minimum of PhD, in a scientific discipline and/or 5+ years of industry with knowledge of toxicology applications
Experience working in a matrixed team environment at a pharmaceutical company and/or CRO
Broad scientific knowledge including pharmacology, toxicology, pathology, physiology and biochemistry
Expertise developing fit for purpose assays for understanding the mechanism of toxicity of agents including drugs, for biomarker development and application, and for derisking

Senior Scientist Gpgx Early Discovery Resume Examples & Samples

Integrate data from population-scale genetic cohorts as well as diverse types of genetic and non-genetic biomedical data including but not limited to eQTL, pQTL and Epigenome to identify causal Genetics Targets for Cardiometabolic Diseases
Formulate and initiate functional validation studies of Genetics Targets in collaboration with experimental scientists within and outside GpGx
Work with cross-functional teams including disease area biologists, pharmacologists and chemists for execution of the Genetics targets across early discovery pipeline
Strong collaboration and communication skills to interface effectively with wide range of subject matter experts in GpGx, Discovery, Clinical and External Communities
Proven track record and understanding of human genetics in disease areas including cardiorenal, diabetes, heart failure, fibrosis, ocular and/or other metabolic related diseases
Extensive experience in bioinformatics, statistical skills and ability to query databases to analyze large-scale genetic datasets as well as leveraging expression and epigenome database to generate hypothesis around potential causal gene
Strong understanding of clinical/pathobiology functional readout in cardiometabolic diseases for identifying translatable targets based on human genetics
Experience in translating Genetics Findings into functionalization of the target gene to provide insight into biological mechanism
Strong communication, collaboration, and leadership skills

Scientist, Antibody Discovery & Engineering Resume Examples & Samples

Execute multiple strategies for therapeutic antibody discovery utilizing mouse hybridoma as well as various panning technologies
Contribute protein engineering expertise to antigen design as well as to antibody format and sequence optimization engineering
Carry out high throughput antibody sequence isolation, analysis, and classification enabling down-stream antibody screening and selection
Demonstrate strong organizational skills to ensure thorough information tracking in material management systems associated with antibody discovery and engineering processes
Document protocols and foster sharing of expertise as a scientific resource for others in the organization
Display strong teamwork skills as part of the antibody discovery and engineering team to ensure effective communication in a multi-functional team setting
PhD in molecular biology, protein/antibody engineering or related fields with 1+ years of industry experience, or equivalent preferred
Demonstrated experience in antibody or protein engineering and characterization required
Strong mammalian tissue culture and molecular biology skills needed
Experience in the generation of antibodies through hybridoma, phage, yeast, or other panning technology is desired
Immunology research experience as well as experience handling mice would be a plus
This individual must be self-motivated, with a proven record of working in a multi-functional team setting, and is effective in sharing learning and expertise
Strong skills in communication, problem solving, cross-function collaboration, planning, documentation, and organization are required

Scientific Active Equity Knowledge Discovery Team Research Scientist Resume Examples & Samples

A passion for data
The knowledge and drive to code beautiful algorithms
A keen attention to detail and the urge to "finish the back of the drawer."
Boundless creativity and a desire to constantly learn
The view that data science is a team sport
Experience with distributed computing
A Master’s / Ph.D. degree in a quantitative discipline
Talent in applying "street fighting math."
Product management and agile development skills