Senior Scientist, / Senior / Scientist Cover Letter

Please consider me for the senior scientist, / senior / scientist opportunity. I am including my resume that lists my qualifications and experience.

In my previous role, I was responsible for routine analytical testing support to Cell and Gene Process Development activities including cell culture, purification, formulation, and device.

My experience is an excellent fit for the list of requirements in this job:

• In-depth experience developing and/or conducting in vitro antigen presentation assays and T cell expansion for the purpose of studying human T cell responses to self and/or foreign antigens (CD8 T cell focus)
• Previous experience characterizing/phenotyping human lymphocytes and their signaling profiles and analyzing the effects of bispecific molecules
• An in-depth understanding of Flow Cytometry human markers
• Experience with developing pharmaceuticals that target Immunoncology proteins
• Experience developing large protein therapeutics for Cancer or Immunology targets
• Experience supervising research associates and/or working in a matrixed environment
• Previous Immunoncology research focused on Type I interferon stimulatory biology
• Solid publication record is strongly preferred (patents or papers)

In response to your job posting for senior scientist, / senior / scientist, I am including this letter and my resume for your review.

In the previous role, I was responsible for project leadership to data science team by creating appropriate analytical frame works and aligning team to project goals.

Please consider my experience and qualifications for this position:

• Doctorate or equivalent in nutrition or other closely related fields (physiology)
• Knowledge of physicochemical characterization of organic and/or inorganic materials
• Travel up to 10 percent (including international)
• Obtains resources needed to complete project deliverables
• Maintains knowledge of FDA and EPA requirements for current projects
• Develops and validates methods for laboratory instruments
• May serve as technical expert in support of plant operations
• Give presentations within and outside R&D

I submit this application to express my sincere interest in the senior scientist, / senior / scientist position.

In my previous role, I was responsible for consultative technical/analytical and functional support in the area of Contract Management/Administration for the project management, project controls, and construction management processes for the Delivery Projects & Construction (DP&C) Organization.

Please consider my experience and qualifications for this position:

• Experience working with MS Visio and Project
• Experience with ELISA and immunoblotting techniques is essential
• Experience operating in a collaborative, team-oriented, multi-disciplinary environment
• PCR, NGS, CE, bottom-up proteomic LCMS experience preferred
• Familiarity with and commitment to GLP and GDP practices relevant 21 CFR Part 11 requirements
• Attractive track record of innovative research and scientific publications in areas of liver diseases
• Proven hands-on experience with liver disease animal models including diabetes, NASH, fibrosis and cirrhosis is essential
• Strong knowledge in molecular biology/biochemistry is preferred

In response to your job posting for senior scientist, / senior / scientist, I am including this letter and my resume for your review.

In the previous role, I was responsible for strategic and scientific oversight to PA Biologics Testing Solutions business and support global biologics strategy, which includes the Cell and Gene Therapy market in particular, as well as molecular biology, virology, analytical and process validation, manufacturing of cell banks, vaccines and other areas.

Please consider my experience and qualifications for this position:

• Ensure high safety standards
• Skills and experience from related process development disciplines including purification, application of bioreactor analytical techniques or pilot scale operations are also valued
• Strong understanding of new scientific concepts and ideas
• Excellent grasp of sterile techniques
• In-depth and broad experience in Bioanalytical techniques as they apply to Biologics Product Quality and related process impurities
• Experience in electrophoresis (Capillary and traditional gel technique)
• Experience with chromatography techniques (HPLC, UPLC, IEX, preparative LC) with multiplemodes of detection including UV, FL, MS, MALLS and RI
• Experience in immunoassays (ELISA, 1D and 2D western blots)

I submit this application to express my sincere interest in the senior scientist, / senior / scientist position.

In the previous role, I was responsible for customer facing demonstrations of Lonza cell and gene therapy manufacturing processes including CAR-T, Natural Killer (NK) and Hematopoietic Stem Cells (HSCs) processes within the cocoon.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Establish, maintain and follow IACUC protocols
• Ensure personal safety and others safety in the work place
• Independently design, conduct, and interpret environmental exposure and drinking water assessments for BCS products in accordance with EPA(US) and PMRA (Canadian) regulatory modelling methods, from baseline assessments to high tier investigations
• Evaluate field and laboratory environmental fate study results to derive quantitative degradation kinetics using North American and European regulatory methodologies
• Evaluate field runoff, leaching, dissipation, spray drift and similar studies with regard to chemical fate and transport for purposes of refining exposure assessments
• Use basic to intermediate GIS skills when performing exposure assessments and work with advanced users in the team for higher tier projects
• Serve as a member of Product Asset Teams by contributing exposure results for strategic decision making to guide business development of BCS active ingredients
• Remain current with technical advances in regulatory exposure modeling, and actively seek ways to bring innovation to EPA and PMRA exposure assessments