Senior Principal Scientist Cover Letter

Please consider me for the senior principal scientist opportunity. I am including my resume that lists my qualifications and experience.

In my previous role, I was responsible for scientific expertise particularly in the areas of omics, chemistry and mass spectrometry as needed by the project.

Please consider my qualifications and experience:

• Strong programming and scripting skills (at least 5 yrs of experience) in (polyglot) of JAVA, C, C++, Python, Perl, R, Matlab, SAS environments
• Prior hands on experience (with examples) with business intelligence stacks, data visualization frameworks (Spotfire, Tableau, Microstrategy ) and integration with big data technologies etc
• A decent understanding of various life science data standards CDISC, OMOP, Mini Sentinel and familiarity with popular databases (Gene Ontology, KEGG, Pathways )
• Execute formulation and process development activities in the area of solid dosage development with specific focus on the spray drying process
• Give support to scale up and tech transfer of the spray drying process in close collaboration with the Janssen Supply Chain
• Identify opportunities for innovation, built further on current enabling technology platforms such as spray drying and expand the best practices
• Built up a strong relationship with collaborating departments and stakeholders such as Pharmaceutical Sciences, Analytical Development, SM API development, Portfolio Management, Clinical Supply Chain, Janssen Supply Chain
• Use his/her global network in order to set up collaborations with external partners and follow-up on Pharmaceutical Development activities

In response to your job posting for senior principal scientist, I am including this letter and my resume for your review.

In the previous role, I was responsible for leadership on individual regional projects with training, mentoring and technical guidance to field technicians to ensure quality of service to all clients throughout the project cycle.

Please consider my experience and qualifications for this position:

• Demonstrated record of practical, translational thinking and accomplishments
• Display solid organization and time management skills
• Proven problem-solving skills and track record of driving change
• Proven experience in design, coordination, analysis and documentation of preclinical studies
• Proficiency with MS Office and common laboratory software (GraphPad Prism)
• Ph.D., MD/Ph.D from an accredited institution in Immunology, Cell Biology, or a closely related area that provides the appropriate background, with strong post-doctoral experience, or equivalent
• Ph.D., MD, MD/Ph.D from an accredited institution with relevant post-doctoural experience
• Experience in experimental pathology, cancer immunotherapy and biomarker research is desirable

I am excited to be applying for the position of senior principal scientist. Please accept this letter and the attached resume as my interest in this position.

In the previous role, I was responsible for technical leadership to project teams within the area of expertise and commits resources to execute specific project tasks.

Please consider my qualifications and experience:

• Reach out to Preclinical, Toxicology, Clinical Pharmacology, Therapeutic Area, Marketing, in order to find opportunities for improved drug product development
• Working knowledge and hands on experience in developing robust in vitro methods
• Background in the validation and life-cycle management of methods and their critical reagents
• Experience in testing and documentation requirements to meet GMP compliance and guidelines
• Conceive and develop technologies to advance business goals internally and through the identification of external collaborative opportunities
• Deliver new product solutions which offer differentiating value to the business, our customers, patients, and the environment
• Ensure appropriate processes are followed for effective and timely engagement of other parts of the company in product development activities
• Knowledge of environmental impact assessment methods, environmental monitoring procedures and protocols, environmental audit protocols, environmental site assessment methods and protocols

I submit this application to express my sincere interest in the senior principal scientist position.

Previously, I was responsible for technical leadership to project teams within area of expertise and commits resources to execute specific project tasks.

Please consider my experience and qualifications for this position:

• Track record of winning work, business development and delivering significant value and successful project outcomes will be preferable
• PhD in Engineering or in Pharmaceutical Sciences, Chemistry (analytical/organic), Physics, or a related science
• Extensive experience with expert knowledge of HTS and statistical data analysis
• Experience in experimentation with muscle cells, adipocytes, or hepatocytes, including primary cells and cell lines
• General and working knowledge of glucose and lipid metabolism and related signaling pathways
• Experience with CRISPR/Cas9 or RNAi screens
• Experience with Spotfire
• Service mind-set with highly collaborative and interpersonal skills

I would like to submit my application for the senior principal scientist opening. Please accept this letter and the attached resume.

In the previous role, I was responsible for leadership for implementation of process changes by working with field operations teams -- drive change management and issue resolution related to functional process area of responsibility.

Please consider my experience and qualifications for this position:

• Excellent communication and collaborative skills, and a track record of publications in the field
• Ph.D., MD, MD/Ph.D from an accredited institution with relevant post-doctoral experience
• Experience in leading/mentoring teams
• Expertise in leading scientists in developing and troubleshooting fit-for-purpose immune-based assays such as ELISA and cells based methods novel platforms
• Experience in preparation of regulatory submission documents such IND, CTAs
• Excellent communication skills in an inter-disciplinary environment - both orally and written
• Experience working in a GLP/GCP environment
• Experience with immunological techniques (ELISA, Luminex and other cell based assay) is also desirable