Computational Scientist Cover Letter

Please consider me for the computational scientist opportunity. I am including my resume that lists my qualifications and experience.

In the previous role, I was responsible for on-site support to DoD HPC users in the CWO Computational Technology Area (CTA).

Please consider my qualifications and experience:

• Good international network in the computational biology community
• A strong understanding of image processing literature and concepts
• Proven expertise in developing efficient, effective image-processing algorithms
• Strong coding skills in C or C++, with experience with iOS or other mobile systems
• PhD in Cancer Genomics, Computational Biology, Bioinformatics, or similar
• Deep understanding of cancer genomics
• Understanding of immuno-oncology, with a knowledge of the current drug landscape
• Demonstrated leadership in directing novel research efforts using genomic data

I would like to submit my application for the computational scientist opening. Please accept this letter and the attached resume.

Previously, I was responsible for support for simulation and forecast of atmospheric variability (e.g., temperature, winds, pressure, relative humidity, cloud cover, precipitation, storms, aerosols and trace chemicals, surface fluxes, etc.) and oceanic variability (e.g., temperature, salinity, currents, tides, waves, ice motion and concentration, sediment transport, optical clarity, etc.).

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Prefer Ph.D
• Experience with computer simulations, data analytics, computational tools, high-performance computing software, and supercomputing hardware
• Knowledge of Linux-based environments
• Record of publishing peer-reviewed research results
• Established record of managing programming projects and research collaborations
• Processing, depth/disparity estimation, optical flow, object tracking, image registration
• Strong coding skills in C, C++, and Python
• Basic knowledge of Objective-C

I submit this application to express my sincere interest in the computational scientist position.

In my previous role, I was responsible for hardware and software support for high-performance computing systems, large scale simulations and data analysis in many disciplines.

Please consider my experience and qualifications for this position:

• Technical proficiency in Python and NGS data processing/analysis
• Experience with neo-antigen identification and/or immunogenicity prediction
• Advanced programming expertise in Python and proficiency in R
• Prior success in the design and development of complex data analysis pipelines and systems
• Experience contributing to (ideally leading) scientific software development efforts to deliver pipelines, tools, and data analyses
• Experience working in a cloud computing environment using Amazon Web Services (EC2 and S3), Docker, Luigi, pandas, and/or Spark
• Proficiency in several genomic data analysis tools such as GATK, Samtools, Bowtie, AnnoVar, , biological pathway/functional analysis
• PhD in Chemistry and/or modeling

I submit this application to express my sincere interest in the computational scientist position.

In the previous role, I was responsible for leadership in the definition and design for HPC systems upgrades, replacements and acquisitions of new generations of UA HPC;.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Knowledge and experience with standard & advanced modeling Tools (in coupling of different methods)
• Capacity to manage a small team of researcher in his domain of expertize
• Capacity to connect with Academia and manage the network
• Experience with protein modeling software packages (MOE, Discovery Studio, Schrodinger, Rosetta)
• Experience in programming or scripting
• Expertise in the use of various programming languages used in scientific high performance computing (FORTRAN, C/C++, Perl, Python), scientific visualization software (e.g., EnSight), and mesh generation software
• Extensive knowledge of at least one scripting language, Python, Perl, , and of relational databases
• Experience installing and supporting bio and chemistry codes (NAMD, AMBER, Matlab, Gromacs, DESMOND) and laboratory equipment such as sequencers

I submit this application to express my sincere interest in the computational scientist position.

In my previous role, I was responsible for hands- on support to the user community regarding optimal use of DSRC infrastructure and assist users with adapting their codes to new HPC platforms.

Please consider my experience and qualifications for this position:

• Demonstrated leadership in both research and development
• Experience in Structure- and Ligand- Based Design, Molecular Modeling, Molecular Dynamics, docking, using expert modeling systems such as the Schrodinger and MOE software suites preferred
• A solid understanding of computational chemistry and ligand or protein modeling methodologies including docking, pharmacophore modeling, similarity searching, QSAR, protein modeling, homology modeling, molecular dynamics and application of these technologies in solving drug discovery problems
• Experience in cheminformatics and bioinformatics
• Experience in the use of expert modeling systems such as Rosetta, Spotfire
• Experience in Knime and scripting capabilities
• Strong track record of research accomplishment in the area of computational chemistry with three or more scientific publications or conference presentations
• Understanding of the physical chemical properties of small-molecules and its interactions with proteins