Protein Scientist Job Description
Protein scientist
provides DNA vector manipulation including expression vector design, DNA/protein sequence analysis, DNA recombination, mutagenesis and plasmid preparation.
Protein Scientist Duties & Responsibilities
To write an effective protein scientist job description, begin by listing detailed duties, responsibilities and expectations. We have included protein scientist job description templates that you can modify and use.
Sample responsibilities for this position include:
3+ years of experience in developing and validating immunoassays –And/Or– Enzyme assays –And/Or– peptide LC/MS –And/Or– protein expression and purification –And/Or– protein characterization
The successful candidate will possess a strong background in cell biology and cell culture with a focus on mammalian transient protein expression
Development, optimization, validation, application and transfer of analytical methods including HPLC
Has a working knowledge of Biosimilar development ideally and must have an in-depth knowledge of analytical techniques used for antibody/protein analysis
Work as part of a team to deliver methodologies, liaise with Clients and interpret a wide variety of analytical results
Characterization of therapeutic proteins (recombinant proteins expressed in eukaryotic and prokaryotic cells)
Independent and thorough work on scientific projects and optimization of existing methods (independent literature research, planning and execution of experiments, evaluation and documentation of results)
Development and implementation of new technologies
Maintenance of laboratory infrastructure / equipment, mass spectrometer, HPLC systems
Contribution to the preparation of submission dossiers
Protein Scientist Qualifications
Qualifications for a job description may include education, certification, and experience.
Licensing or Certifications for Protein Scientist
List any licenses or certifications required by the position: GMP, GLP
Education for Protein Scientist
Typically a job would require a certain level of education.
Employers hiring for the protein scientist job most commonly would prefer for their future employee to have a relevant degree such as Bachelor's and Master's Degree in Biochemistry, Chemistry, Biology, Molecular Biology, Biotechnology, Engineering, Science, Cell Biology, Chemical Engineering, Biophysics
Skills for Protein Scientist
Desired skills for protein scientist include:
Construct design
Molecular biology
Protein expression
Purification
Analytical
Antibody technologies
Biochemistry in a R&D environment
Characterization and structure function
DNA sequence analysis software
Field of allergy research and work experience in product development desirable
Desired experience for protein scientist includes:
PhD degree in (molecular) biology, biochemistry, biophysics or related fields
Presentation of results in local and global project teams
Writing of internal scientific reports and publications for peer-reviewed journals
University degree in Chemistry, Pharmacy, Biology or other natural sciences, preferably PhD (advanced degree in natural sciences and/or further education)
2 - 4 years of experience in the biopharmaceutical industry or in an equivalent environment
Expert knowledge of (glyco-) protein analytics, especially in the area of electrospray ionization mass spectrometry and/or capillary electrophoresis
Protein Scientist Examples
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Protein Scientist Job Description
Job Description Example
Our growing company is looking for a protein scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for protein scientist
- Protein purification from E
- Primary responsibilities for designing our next generation of protein therapeutics, including but not limited to expression, purification, biophysical characterization and cell-based activity assays
- Lead Protein Science Efforts in designing constructs, high through put expression screening strategies, purification and characterization of various recombinant protein targets including membrane proteins and multi-protein complexes to enable generation of high quality proteins for screening and structure determination
- Participates on cross-functional teams by performing assigned experiments and offering technical advice at team meetings
- The candidate will participate in generating forced degradant of the protein product for structure/function characterization
- Fundamental knowledge of proteins and antibodies
- May interface with partner organizations both inside and outside of Process Sciences
- Hands-on development of LC/MS/MS methods to quantify peptide and protein therapeutics and biomarkers in biological matrices such as serum
- Review study protocols and reports
- Develop technical solutions to problems, keep abreast of industry best practices and technological advancements in biologics manufacturing and utilizes those to further enhance department’s capabilities
Qualifications for protein scientist
- Open minded, excellent communication skills, reliable, team player
- Excellent oral and written communication skills, and good presentation skills
- PhD or equivalent experience in a related field
- Demonstrates a broad knowledge of field
- Good understanding of immunology/oncology and drug development process is a plus
- OAbility to execute, document, and schedule cGMP manufacturing activities
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Protein Scientist Job Description
Job Description Example
Our growing company is searching for experienced candidates for the position of protein scientist. If you are looking for an exciting place to work, please take a look at the list of qualifications below.
Responsibilities for protein scientist
- Lab based scientist with science leadership skills taking a lead role in the innovation, design and delivery of potential therapeutic proteins
- A key aspect of this position will be communication both within the Protein Science team and across multiple disciplines (project teams, antibody discovery, intellectual property and clinical production teams) ensuring that information on work progress is relayed in a clear manner, highlighting any technical issues/opportunities and providing potential solutions
- A major component of the role involves understanding the protein needs of early stage projects and therapeutic area scientists along with coordination of delivery with project teams
- Communicate own work within organization externally
- Express and purify proteins to support assay development, HTS screen, biophysical assays and crystallization
- Critically QC protein reagents for different applications
- Closely work with project biology group to understand project needs and design proper experiments
- Read literature to provide clone design ideas and other protein biochemistry suggestions
- Evaluate scientific literature critically and adopt novel technologies to facilitate research
- Work independently on the design, execution, and interpretation of experimental results
Qualifications for protein scientist
- OAbility to operate within a clean room environment
- Good knowledge of cheminformatics and/or structural biology approaches desirable
- Bachelors or Master’s degree in Biochemistry, Chemistry, Analytical Chemistry with 3-5 years of related industry experience
- Familiar with scripting languages such as Python, Perl, bash
- Familiarity with data mining / web scrapping tools is a plus
- Familiarity with Statistical Analysis of Large Datasets
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Protein Scientist Job Description
Job Description Example
Our growing company is looking to fill the role of protein scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for protein scientist
- Will be involved in establishing Development & Establishment scope with Client
- Will produce study protocols and reports to meet client and regulatory requirements
- Responsible for Gap Analysis as appropriate when Developing/Establishing methods
- Involved in start-up and ongoing study meetings
- To be aware at all times of study status and anticipate problems that may affect timing, quality etc and to work with operations taking appropriate action to resolve such problems and prioritise analysis for clients
- Provides client feedback to team
- Responsible for providing methods post establishment as confirmation of readiness for Qualification
- Responsible for set up of appropriate software (Softmax Pro, Empower etc)
- Hosts and participates in scientific client visits
- Ensures that their individual training records are up to date and accurately reflect their capabilities
Qualifications for protein scientist
- Comfortable meeting deadlines in a fast paced biotech environment
- Sound understanding of the latest genomics technologies and methodologies
- Masters’ degree in Biology and/or Bachelor’s degree in Biopharmaceuticals plus two (2) to four (4) years’ experience required/
- GMP clinical manufacturing
- Particular expertise and interest in protein homeostasis, hematologic malignancies especially MDS, bone marrow biology, and immunology is sought along with skill in associated assay methods
- Bachelor’s degree, from an accredited institution, with four (4) to six (6) years relevant experience OR Master’s degree, from an accredited institution, with two (2) to four (4) years relevant experience OR Doctoral degree, from an accredited institution with at least two (2) years relevant experience
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Protein Scientist Job Description
Job Description Example
Our company is growing rapidly and is searching for experienced candidates for the position of protein scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for protein scientist
- Performs any other task as may be reasonably requested by the BioCMC Management
- Conduct hands on bench development prototypes ensuring products meet target cost, sensory, regulatory and quality compliance consumer acceptance criteria
- Conduct laboratory operations in a safe manner
- Prosecute novel therapeutic proteins to demonstrate proof-of-principle using in-house capabilities external resources (CROs)
- Support IP protection and publications
- Work as part of a scientific team
- Interface with colleagues in various therapeutic areas, Screening, Pharmacology and Structural Chemistry to design a comprehensive reagent generation strategy to enable lead ID and lead optimization efforts
- Devise, perform and/or oversee studies for scale-up and optimization of protein-based reagent production, and prepare reports of such studies for regulatory submissions
- Act as liaison between OPKO and critical suppliers
- Act as liaison between OPKO and reagent users (CLIA laboratories and in-house Quality Control lab) to monitor ongoing performance of marketed tests, provide education on proper usage, and provide support in the event of adverse events
Qualifications for protein scientist
- Requires a minimum education of a Bachelor’s degree in Biochemistry, Chemistry, Chemical Engineering, or a closely related discipline
- Minimum of one year experience overseeing employees and projects
- Physical Demands / Surroundings – Works in an office or lab setting under desirable conditions with few or no disagreeable features
- Extensive experience with general molecular biology skills such as PCR amplification and primer design, gel electrophoresis, ligations, bacterial transformations, mini and maxi-prep plasmid isolation, and DNA sequence analysis is required
- Experience with next generation sequencing technologies or high throughput cloning technologies is a plus
- Proven experience and knowledge of recombinant antibody construction and design is desirable
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Protein Scientist Job Description
Job Description Example
Our growing company is looking for a protein scientist. To join our growing team, please review the list of responsibilities and qualifications.
Responsibilities for protein scientist
- Closely collaborating with team members with analytical development and process biochemistry departments to plan development activities and troubleshoot challenges
- Develop the practical knowledge base, skills and experience required to execute developed DNA production, cell transfection, fermentation, induction, purification and assay procedures independently within 12 months of starting employment
- With supervisory guidance, aid in the generation of new DNA production, cell transfection, fermentation, induction, purification and assay procedures as may be required
- Be familiar with the use and operation of all laboratory equipment and software used by the Protein Expression & Conjugation group
- Manage data collection and tracking from assay use in the field and report on trending analysis to the development team, manufacturing, QC, and QA
- Interface regularly with the manufacturing team, QC, and QA to facilitate transfer of assay improvements to manufacturing and contribute to technical documentation
- Executing on assays and with supervisor, plan experiments
- Maintaining equipment and ensure laboratory safety by identifying problems and completing regular evaluations
- Participating in tracking biological/medical samples
- Performing immunoassays on different platforms including plate ELISA, Simoa, Meso Scale, Envision and others
Qualifications for protein scientist
- Proven track record in Purification Process Development is necessary with emphasis on chromatographic separations and excellent understanding of and experience with chromatographic resin screening and process optimization
- The successful candidate is a team player with strong data management, organizational and communication skills
- Primary responsibilities include method development and routine analytical analysis for protein therapeutics such as SEC, IEC, RP-LC, icIEF, SDS-PAGE, glycan analysis, intact mass analysis and peptide mapping etc using state of the art separations technology and mass spectrometry instrumentation
- PhD degree in Analytical Chemistry, Biochemistry, Pharmaceutical Science or related field
- 0-3 years of industry experience in analytical research and development of protein therapeutics
- Hands-on experience in various analytical techniques for glycoprotein characterization such as SEC, IEX, RP-LC, LC-MS, CE and icIEF