Principal Research Scientist Job Description

Principal Research Scientist Job Description

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Principal research scientist provides expert knowledge of administrative databases and other sources of data and appropriate use and limitations.

Principal Research Scientist Duties & Responsibilities

To write an effective principal research scientist job description, begin by listing detailed duties, responsibilities and expectations. We have included principal research scientist job description templates that you can modify and use.

Sample responsibilities for this position include:

Lead a systems immunology research group responsible for identifying novel targets and pathways to stratify and treat chronic inflammatory and autoimmune diseases
Continually monitor research frontier and technology trends
Participate in the development of patent applications
Contribute in clinical scientific discussions with regulatory agencies / notified bodies to drive support of the clinical and regulatory strategy, including proposed clinical investigations
Ability to collaborate across different functional areas within CR&D to ensure alignment with governance processes (assigning roles and responsibilities, setting priorities, managing deliverables, etc)
Analyze IC intelligence capabilities to assess gaps/shortcomings of existing systems
Conceive, execute and champion novel target validation strategies to build drug discovery programs in the field of immuno-oncology
Identify emerging clinical trends and develop novel target identification strategies to leverage these developments
Help drive development of comprehensive strategy to build an early immuno-oncology portfolio of drug discovery programs utilizing both small molecule and biologics based approaches
Design small molecule and antibody screening strategies, execute screening funnel and direct functional studies toward target validation

Principal Research Scientist Qualifications

Qualifications for a job description may include education, certification, and experience.

Licensing or Certifications for Principal Research Scientist

List any licenses or certifications required by the position: DABT, CISSP, ECVP, ACVP

Education for Principal Research Scientist

Typically a job would require a certain level of education.

Employers hiring for the principal research scientist job most commonly would prefer for their future employee to have a relevant degree such as Master's and Bachelor's Degree in Education, Science, Engineering, Computer Science, Chemistry, Medicine, Sciences, Graduate, Statistics, Electrical Engineering

Skills for Principal Research Scientist

Desired skills for principal research scientist include:

Good Laboratory Practices regulations
Biostatistics
Related disciplines
Immunology
Data analysis
Data collection
Principles of quantitative and qualitative research design
Statistics
Administrative databases and other sources of data and appropriate use and limitations
Applicable international guidelines for all types of studies

Desired experience for principal research scientist includes:

Hands on” experience in design, development and manufacture of amorphous solid dispersion formulation
Experience working as a Government or contractor employee with an organization whose primary mission is basic research and development (e.g., DoD 61XX or 62XX program areas)
Demonstrated technical excellence and expertise in translational medicine
Experience in the development and utilization of biomarkers, various technologies/platforms (–omics technologies, immunohistochemistry and immunoassays)
Ability to lead translational efforts and cross functional teams
Demonstrated effective interpersonal and written/verbal communication skills

Principal Research Scientist Examples

1

Principal Research Scientist Job Description

Job Description Example
Our innovative and growing company is looking for a principal research scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for principal research scientist
  • Participate in Kick-Off Meeting, Preliminary Design Reviews, Critical Design Review, (Requires travel)
  • Leads and coordinates highly technical presentation of results to clients, regulators, stakeholders, and in public forums
  • Train, mentor and lead junior technical staff
  • Participates in the development of materials for presentation of results to clients, regulators, and stakeholders and in public forums
  • Expect around an 85/15 percent split in work between Chemical Engineering and our Chemical Lab
  • Travel (50%) to various CONUS locations for business related purposes and off-site training is expected
  • Defining and leading the toxicology strategy for livestock programs
  • Act as a GLP principal investigator/contributing scientist (pathology)
  • Pathology peer review of outsourced toxicology and target animal safety studies
  • Interpretation and communication of data to project teams and senior management
Qualifications for principal research scientist
  • Expert knowledge of data analytics platforms and software
  • Expertise in data analytics methodology and algorithms
  • Expertise in scientific computing principles
  • Fluency in multiple programming languages, compilers and operating systems
  • Experienced in working with biomedical data
  • Basic understanding of drug discovery and development
2

Principal Research Scientist Job Description

Job Description Example
Our company is growing rapidly and is hiring for a principal research scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for principal research scientist
  • Collaboration with toxicologists and research scientists to elucidate toxicology findings of concern and with in-vivo animal model development/interpretation
  • Project team representative for toxicology supporting human food safety
  • Lead drug discovery project teams and champion projects from discovery into early clinical development
  • Develop and characterize innovative preclinical animal models that enable the interrogation of mechanism of action of immune therapies dedicated to drug discovery and development projects
  • Manage direct reports, including scientists and research associates
  • Develop strategies and methodologies to analyze publically available and in-house complex clinical, molecular and immune data sets
  • Sources and identifies emerging scientific trends from multiple internal and external sources and assess relevance
  • Provide impartial technical guidance and mentoring across multiple fields
  • Bring a multifaceted approach to problem solving at technology and product levels
  • Keep abreast of current state-of-the-art technical literature
Qualifications for principal research scientist
  • Bachelor of Science degree in engineering or relevant field and at least 8-10 years’ experience focused on intelligence or other analytic efforts and 4 years business or program management experience
  • Must be a US citizen with an active SECRET DoD Security Clearance
  • Bachelor’s degree in Chemistry or equivalent scientific field of study with minimum of eight (8) years analytical laboratory experience or a MS with five (5) years equivalent experience with a minimum of two (2) years direct analytical experience using ICP-MS, ICP-AA or equivalent technology for analysis of metals
  • Excellent PC skills which may include database entry/management
  • Bachelor’s degree in Computer Engineering, Computer Information Systems or technical related field and 10 years directly related experience
  • Excellent writing and communications skills, to include the ability to render concise reports, summaries, and formal oral presentations, and MS Office capability
3

Principal Research Scientist Job Description

Job Description Example
Our company is looking to fill the role of principal research scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for principal research scientist
  • Continually challenge, develop capability and best practice and drive new ways of technical thinking across the wider community
  • Deliver specialist knowledge to the senior management team in research reviews
  • Act as an independent reviewer and chair technical reviews at key stage gates
  • Contribute scientific and technical expertise to multiple project teams focused on Neuroinflammation and Neurodegeneration
  • Identify unmet technical, scientific and clinical diagnostic needs that create new opportunities for Cell Analysis
  • Provide technical, scientific and user insights to drive best products throughout the development cycle
  • Scientific and technical leadership for innovation activities
  • Consults to principal scientists in the planning and conduct of the study, in the analysis of data, and the interpretation of findings
  • Organizes and manages all statistical aspects of successful research projects
  • Provides responsible, competent technical advice to project and operations management
Qualifications for principal research scientist
  • Must be a US Citizen with the an active Top Secret / Secret Compartmented Information (TS/SCI) clearance with a JPAS Validation of Security Clearance Investigation Date within the past five years
  • Must be a US citizen with the ability to obtain and maintain a DoD clearance
  • Master’s degree or higher in health informatics, public health, other health-related relevant field
  • Master’s degree in Chemical Engineering with at least five (5) years of Chemical Engineering work experience
  • PhD in Human Factors Engineering, Human Factors Psychology, Experimental Psychology, Cognitive Psychology, or Cognitive Systems Engineering with 2-5 years of experience working in the medical product (preferred), commercial, or industrial sectors
  • Proven experience in of the following areas
4

Principal Research Scientist Job Description

Job Description Example
Our growing company is looking for a principal research scientist. Please review the list of responsibilities and qualifications. While this is our ideal list, we will consider candidates that do not necessarily have all of the qualifications, but have sufficient experience and talent.
Responsibilities for principal research scientist
  • Support preparation, presentation, and submission of research grant and contract proposals
  • Organizes and leads successful research projects in strategic areas (current emphasis on current emphasis on marijuana use and the overlap of marijuana and tobacco use), or with strategic clients, ideally providing support for a number of exempt and nonexempt staff
  • Collaborate with scientists within and outside the department in identifying, defining and executing R&D goals
  • Serve as a role model for effective communication
  • Demonstrate awareness of overall departmental budget
  • Ensure that all group members are trained and comply with all regulations and policies
  • Ability not only to lead, but to also work constructively with leadership or other team members when their opinions/decisions diverge from the candidate’s own opinion is critical
  • Performs complex assignments by compiling and evaluating design and test data, preparing technical specifications, analyzing technical data to determine appropriate limits and variables for product, process or materials specifications
  • Analyzes and interprets data collected
  • Troubleshoots complex testing processes when expected results are not obtained
Qualifications for principal research scientist
  • Must be willing to travel up to 20% both domestic and international
  • Bachelor’s degree and 8 or more years of experience
  • Master’s degree or higher in economics or other relevant social science field and at least five years of experience
  • Expertise in Stochastic Processes
  • Track record of recent scientific publications and high level of proficiency with multi-color flow cytometry and mechanistic studies of immune regulation
  • Expertise in extending discovery research through translational human biology to clinical development, using bioinformatics approaches
5

Principal Research Scientist Job Description

Job Description Example
Our innovative and growing company is looking for a principal research scientist. Thank you in advance for taking a look at the list of responsibilities and qualifications. We look forward to reviewing your resume.
Responsibilities for principal research scientist
  • Assists with proposal efforts
  • Contributes to IR&D studies
  • Lead innovative analytical research in emerging contaminants (including PFAS compounds) to solve highly complex environmental problems, including new method development
  • Maintain formal and informal communications and relationships with clients that have interest in emerging contaminants, and keep current on emerging contaminant literature, to ensure research is relevant to evolving challenges
  • Provide direction to and coordinate the efforts of technical staff in the performance of assigned research and projects
  • Compile and evaluate test data, prepare technical specifications or modifications, and analyze and interpret results
  • Lead and/or contribute to proposal efforts to government and industrial clients
  • Perform aerosol exposure studies
  • Perform and supervise biological decontamination procedures for Class III biosafety cabinets post-aerosol
  • Maintain and calibrate aerosol systems
Qualifications for principal research scientist
  • Demonstrated skills and experience with LC-MS/MS instrumentation
  • Minimum two years of industrial experience
  • Fluency in Python, Perl, or another scripting language desired
  • PhD in molecular biology, virology, microbiology, or life sciences with at least 2-5 years’ experience testing vaccines and therapeutics against infectious diseases, especially biosafety level 3 (BSL-3) biological agents
  • Demonstrated experience and knowledge of in vitro models and their application to therapeutic research
  • Demonstrated experience working with influenza virus

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