Scientist, Process Development Cover Letter

I submit this application to express my sincere interest in the scientist, process development position.

In the previous role, I was responsible for on-floor technical support for cell culture manufacturing including routine process monitoring/trending, and troubleshooting of any process issues.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Experience with electronic notebook systems
• Experience with procedures for the isolation, transduction/activation, expansion and cryopreservation of gene modified patient derived cells
• Works in laboratory and production environments with potential exposure to occupational hazards including chemical cleaners, biohazardous materials, noise, mechanical and heat/cold energy
• BS/MS or PhD in biology, biochemistry, immunology, bioengineering, or related field
• HND/BSc in Biology/ Biochemistry/Biotechnology/Biochemical Engineering or related subject
• Understanding of the principles of chromatography and other techniques associated with protein purification, associated analytics
• Protein chemistry experience
• Adaptable and a team player with a conscientious attitude and enthusiasm

I submit this application to express my sincere interest in the scientist, process development position.

In my previous role, I was responsible for purification support for cell line/cell culture development activities and material generation to enable formulation and analytical development supporting customer workflows.

My experience is an excellent fit for the list of requirements in this job:

• Perform experiments to evaluate and implement innovative
• Relevant working knowledge and hands-on experience in area executing technical projects related to production / purification of large molecules
• Proficient knowledge and hands-on experience of various platforms used for suspension cultures and adherent cultures (focusing on bioreactors)
• Excellent oral and written communication skills that have been demonstrated through presentations/seminars, implementation of new services, Excellent skills in applicable computer programs
• Effective training skills for complex and highly technical work
• Exposure to 3L to 20L bioreactor operations and/or cultivation in associated platforms such as agar plates, spinner/shake flasks, or T-flasks
• General laboratory skills, aseptic technique, experience with pipettes, and experience with automation
• Prior statistical analysis experience

I would like to submit my application for the scientist, process development opening. Please accept this letter and the attached resume.

In the previous role, I was responsible for technical expertise for cell culture processes and Pall single-use bench- and large-scale bioreactor systems internally and for life science companies.

My experience is an excellent fit for the list of requirements in this job:

• Experience working with laboratory automation or advanced computer-controlled laboratory equipment, such as bioreactor controllers
• Experience in Lean Six Sigma & DOE tools and statistical analysis preferred
• Able to work with advanced techniques in either cell culture (cell counting, subculturing, preparing media, etc)
• Experience with large scale manufacturing support (mammalian preferred), current Good Manufacturing Practices, US/EU regulations
• Large molecule process development, or relevant, experience including scaling (up and down) and tech transfer of upstream large molecule drug substance processes (aseptic-flasks, bioreactors, single use systems)
• Subject Matter Expertise with Upstream lab or pilot-scale fermenters/bioreactors/cell culture running microbial and/or mammalian cell based large molecule processing
• Advanced proficiency in chromatography, membrane filtration operations, and common biochemical analytical techniques
• Bachelors in Biochemistry, Biotechnology, Analytical Chemistry or a related discipline

I would like to submit my application for the scientist, process development opening. Please accept this letter and the attached resume.

Previously, I was responsible for guidance and support throughout projects and product builds; Such as cell culture, cell transfection, mammalian tissue culture, all cell culture aspects using proper aseptic techniques, microbiological principle of contamination, protein purification, antibody detection production of different product lines, QC, using laboratory equipment’s for each process etc.

My experience is an excellent fit for the list of requirements in this job:

• Strong background in statistics and proficient with statistics software
• Working knowledge of intellectual property and writing patents
• Knowledge of simple distillation, vacuum distillation and fractional distillation of complex multi-component organic waste streams
• In depth knowledge of organic chemistry
• Providing technical guidance on complex issues requiring independent and/or teamwork analysis and judgment
• Development of material balances
• Develop process flow diagrams (PFDs)
• Experience with process start-up

Please consider me for the scientist, process development opportunity. I am including my resume that lists my qualifications and experience.

Previously, I was responsible for laboratory based technical support for a large scale perfusion mammalian cell culture manufacturing process.

I reviewed the requirements of the job opening and I believe my candidacy is an excellent fit for this position. Some of the key requirements that I have extensive experience with include:

• Experience with Design of Experiments (DOE), and Lean Six Sigma principles
• Experience in using software and statistical tools (JMP, Spotfire, SIMCA) for data mining, data analysis, modeling and statistical process control (SPC)
• Develop and optimize biologics and/or vaccine processes for in-line and network products
• Support laboratory scale process characterization studies for future products
• Write and review technical documents, including regulatory filings
• Work both independently and within multidisciplinary teams including scientists, engineers and site leaders
• Produce high quality work against firm deadlines
• Maintain excellence of compliance with safety and environmental regulations