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Postdoctoral position in biosensor design and implementation at the University of Washington
The laboratory of Dr. Liangcai Gu in the Department of Biochemistry and the Institute for Protein Design (IPD) at the University of Washington School of Medicine invites applications for a postdoctoral position in designing metabolite and drug biosensors and applying them to study metabolism and signaling in immune and nervous systems. The position is available immediately.
We use high-throughput screening and computation design approaches to create genetically encoded metabolite and drug biosensors to dissect metabolic and signaling pathways with high spatiotemporal resolution. Particularly, we design chemically induced dimerization (CID) systems to create biosensors by coupling them with optical readouts (e.g., fluorescence and luminescence). We recently demonstrated an efficient, generalizable method (“COMBINES-CID”, Company website.1021/jacs.9b03522) for creating highly specific CID systems. Our method does not rely on finding and modifying natural allosteric ligand binding proteins and is applicable to a large variety of small-molecule targets
Equal Employment Opportunity Statement
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.
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