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The Rare Diseases Drug Discovery Unit (DDU) at Takeda is seeking a highly motivated individual to lead the translational sciences group. In close collaboration with colleagues from within the Therapeutic Area Unit (TAU) this individual will run the internal translational sciences efforts within the Rare DDU. (S)he will provide innovative scientific leadership to manage ongoing efforts and build the team to allow support from target discovery through pre-clinical proof of concept. (S)he will grow and lead a team of scientist from within the Rare Disease DDU, as well as manage collaborations and CROs. This highly cross-functional role will require working with several internal groups to execute programs and determine new directions.
Lead the Rare Diseases Drug Discovery Unit (DDU) translational sciences group by managing a group of scientists and working with several internal groups to develop current programs and establish new programs
Ability to convey the scientific basis of translational sciences to discovery and early development projects and to key internal stakeholders including leadership teams.
Operate and align with key functions (e.g., In vivo sciences, Clinical TAU, DMPK, DSRE) to lead multiple discovery translational programs from early drug discovery into preclinical development.
Coordinate with leadership team to confirm pipeline plans align with strategic goals
Provide leadership, scientific guidance, mentorship and support for group members
Maintain a high level of scientific expertise through continuous literature review, congress attendance, and networking with key opinion leaders
Dissemination of data and information to DDU and other functions as appropriate
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
PhD with 10+ years of relevant experience in the life sciences including biopharma and/or academic group head positions.
Prior experience of leading a group in preclinical translational space
Experience leading rare disease drug discovery and/or early development programs preferred
In-depth knowledge and expertise in translational target discovery and validation required
Excellent communication and presentation skills to convey scientific details to internal groups with various skill sets is essential
Track record to demonstrate ability to work and complete projects required e.g. peer-reviewed publications, patents.
Deep understanding of rare disease research, including tools, assays, models, and technologies suitable for prosecuting drug discovery projects
Demonstrates ability to work across functions and cultures
Willingness to travel to meetings or client sites, including overnight and weekend trips. Some international travel may be required.
Requires approximately 10% travel
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Employment / Recruitment agents may only submit candidates for vacancies only if they have written authorization to do so from Shire, a wholly-owned subsidiary of Takeda’s Talent Acquisition department. Any agency candidate submission may only be submitted to positions opened to the agency through the specific Agency Portal. Shire, a wholly-owned subsidiary of Takeda will only pay a fee for candidates submitted or presented where there is a fully executed contract in place between the Employment / Recruitment agents and Shire, a wholly-owned subsidiary of Takeda and only if the candidate is submitted via the Agency Portal. Candidates submitted or presented by Employment / Recruitment Agents without a fully executed contract or submitted through this site shall not be deemed to form part of any Engagement for which the Agency may claim remuneration.
Equal Employment Opportunity
Shire, a wholly-owned subsidiary of Takeda, is an Equal Opportunity Employer committed to a diverse workforce. Shire, a wholly-owned subsidiary of Takeda, will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.
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Shire, a wholly-owned subsidiary of Takeda, is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.
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